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Haus6 Gene Detail
Summary
  • Symbol
    Haus6
  • Name
    HAUS augmin-like complex, subunit 6
  • Synonyms
    6230416J20Rik, D4Ertd27e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923389
    NCBI Gene: 230376
  • Gene Overview
    MyGene.info: HAUS6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:86578855-86612055 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 40.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923389
protein coding gene Chr4:86578855-86612075 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028412
protein coding gene Chr4:86341437-86374658 (-)
A/J MGP_AJ_G0028373
protein coding gene Chr4:83334113-83367391 (-)
AKR/J MGP_AKRJ_G0028322
protein coding gene Chr4:85433324-85466645 (-)
BALB/cJ MGP_BALBcJ_G0028393
protein coding gene Chr4:83517270-83550482 (-)
C3H/HeJ MGP_C3HHeJ_G0028108
protein coding gene Chr4:86082178-86115532 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028832
protein coding gene Chr4:89613049-89646912 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026132
protein coding gene Chr4:79427571-79461469 (-)
CAST/EiJ MGP_CASTEiJ_G0027549
protein coding gene Chr4:83985797-84021382 (-)
CBA/J MGP_CBAJ_G0028077
protein coding gene Chr4:92399975-92433518 (-)
DBA/2J MGP_DBA2J_G0028226
protein coding gene Chr4:83077993-83111720 (-)
FVB/NJ MGP_FVBNJ_G0028192
protein coding gene Chr4:82065827-82099025 (-)
LP/J MGP_LPJ_G0028326
protein coding gene Chr4:86676516-86709739 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028221
protein coding gene Chr4:97453402-97487420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028869
protein coding gene Chr4:85507089-85540307 (-)
PWK/PhJ MGP_PWKPhJ_G0027272
protein coding gene Chr4:81423282-81457158 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027097
protein coding gene Chr4:83059830-83097923 (-)
WSB/EiJ MGP_WSBEiJ_G0027625
protein coding gene Chr4:85691407-85725905 (-)



Homology
more
  • Human Ortholog
    HAUS6, HAUS augmin like complex subunit 6
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HAUS6, HAUS augmin like complex subunit 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Dgt6, FAM29A
  • Links
    NCBI Gene ID: 54801
    neXtProt AC: NX_Q7Z4H7
    UniProt: Q7Z4H7

  • Chr Location
    9p22.1; chr9:19053137-19102942 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9760
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HAUS6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality between E2.5 and E7.5 with delayed or incomplete clustering of microtubule-organizing centers.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038047 Ensembl Gene Model | MGI Sequence Detail 33201 C57BL/6J ±  kb
transcript ENSMUST00000070607 Ensembl | MGI Sequence Detail 6158 Not Applicable  
polypeptide ENSMUSP00000070504 Ensembl | MGI Sequence Detail 933 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR026797 HAUS augmin-like complex subunit 6
    IPR028163 HAUS augmin-like complex subunit 6, N-terminal
Molecular
Reagents
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  • All nucleic 70
    cDNA 67
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1098820
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:235084 Watanabe S, et al., Intra-spindle Microtubule Assembly Regulates Clustering of Microtubule-Organizing Centers during Early Mouse Development. Cell Rep. 2016 Apr 5;15(1):54-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory