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Depdc1a Gene Detail
Summary
  • Symbol
    Depdc1a
  • Name
    DEP domain containing 1a
  • Synonyms
    5830484J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923381
    NCBI Gene: 76131
  • Gene Overview
    MyGene.info: DEPDC1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:159495433-159529955 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 82.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923381
protein coding gene Chr3:159495416-159529955 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028018
protein coding gene Chr3:163653679-163692650 (+)
A/J MGP_AJ_G0027976
protein coding gene Chr3:157753499-157789526 (+)
AKR/J MGP_AKRJ_G0027942
protein coding gene Chr3:161903320-161937621 (+)
BALB/cJ MGP_BALBcJ_G0027988
protein coding gene Chr3:157548555-157585172 (+)
C3H/HeJ MGP_C3HHeJ_G0027718
protein coding gene Chr3:162289184-162324993 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028431
protein coding gene Chr3:169007408-169047147 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025770
protein coding gene Chr3:152190758-152221252 (+)
CAST/EiJ MGP_CASTEiJ_G0027171
protein coding gene Chr3:162408070-162452241 (+)
CBA/J MGP_CBAJ_G0027693
protein coding gene Chr3:174984505-175024954 (+)
DBA/2J MGP_DBA2J_G0027833
protein coding gene Chr3:156743710-156787320 (+)
FVB/NJ MGP_FVBNJ_G0027800
protein coding gene Chr3:154082491-154122308 (+)
LP/J MGP_LPJ_G0027944
protein coding gene Chr3:165005884-165040961 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027833
protein coding gene Chr3:183808630-183859205 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028490
protein coding gene Chr3:161534966-161568131 (+)
PWK/PhJ MGP_PWKPhJ_G0026894
protein coding gene Chr3:156653782-156689290 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026722
protein coding gene Chr3:159810423-159848139 (+)
WSB/EiJ MGP_WSBEiJ_G0027251
protein coding gene Chr3:162512167-162546938 (+)



Homology
more
  • Human Ortholog
    DEPDC1, DEP domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DEPDC1, DEP domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DEP.8, DEPDC1A, DEPDC1-V2, SDP35
  • Links
    NCBI Gene ID: 55635
    neXtProt AC: NX_Q5TB30
    UniProt: Q5TB30

  • Chr Location
    1p31.3; chr1:68474152-68497221 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9834
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DEPDC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028175 Ensembl Gene Model | MGI Sequence Detail 34523 C57BL/6J ±  kb
transcript ENSMUST00000120272 Ensembl | MGI Sequence Detail 3323 Not Applicable  
polypeptide ENSMUSP00000113216 Ensembl | MGI Sequence Detail 806 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000591 DEP domain
    IPR008936 Rho GTPase activation protein
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory