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Depdc1a Gene Detail
Summary
  • Symbol
    Depdc1a
  • Name
    DEP domain containing 1a
  • Synonyms
    5830484J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923381
    NCBI Gene: 76131
  • Gene Overview
    MyGene.info: DEPDC1
Location & Maps
more
  • Sequence Map
    Chr3:159495433-159529955 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34523 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 82.47 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DEPDC1, DEP domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DEPDC1, DEP domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DEP.8, DEPDC1A, DEPDC1-V2, SDP35
  • Links
    NCBI Gene ID: 55635
    neXtProt AC: NX_Q5TB30

  • Chr Location
    1p31.2; chr1:68474152-68497221 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026469 VEGA Gene Model | MGI Sequence Detail 34523 C57BL/6J ±  kb
transcript OTTMUST00000065448 VEGA | MGI Sequence Detail 3323 Not Applicable  
polypeptide OTTMUSP00000032622 VEGA | MGI Sequence Detail 806 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    84 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029407 DEP domain-containing protein 1A
  • InterPro Domains
    IPR000591 DEP domain
    IPR000198 Rho GTPase-activating protein domain
    IPR008936 Rho GTPase activation protein
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233777 Ray JP, et al., The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20;43(4):690-702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory