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Las1l Gene Detail
Summary
  • Symbol
    Las1l
  • Name
    LAS1-like (S. cerevisiae)
  • Synonyms
    1810030A06Rik, 5830482G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923380
    NCBI Gene: 76130
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:94978941-95000568 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 42.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    459 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923380
 protein coding gene ChrX:94963651-95000580 (-)
129S1/SvImJ ENSMUSG00200037484
 protein coding gene ChrX:76672809-76694388 (-)
A/J ENSMUSG00195030599
 protein coding gene ChrX:80465245-80486841 (-)
AKR/J ENSMUSG00220027369
 protein coding gene ChrX:75205449-75227043 (-)
BALB/cJ ENSMUSG00180021320
 protein coding gene ChrX:77128923-77150516 (-)
C3H/HeJ ENSMUSG00175018877
 protein coding gene ChrX:80823655-80845249 (-)
C57BL/6NJ ENSMUSG00215015916
 protein coding gene ChrX:77349296-77370874 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033249
 protein coding gene ChrX:90488346-90508714 (-)
CAST/EiJ ENSTCUG00005027072
 protein coding gene ChrX:78337538-78359349 (-)
CBA/J ENSMUSG00210034151
 protein coding gene ChrX:77571530-77593123 (-)
DBA/2J ENSMUSG00185031574
 protein coding gene ChrX:90041555-90063134 (-)
FVB/NJ ENSMUSG00205025375
 protein coding gene ChrX:76811191-76832769 (-)
JF1/MsJ ENSUMUG00000021215
 protein coding gene ChrX:110662182-110683285 (-)
LP/J ENSMUSG00230010846
 protein coding gene ChrX:96735963-96757541 (-)
NOD/ShiLtJ ENSMUSG00190017704
 protein coding gene ChrX:76730615-76752193 (-)
NZO/HlLtJ ENSMUSG00225045412
 protein coding gene ChrX:101867224-101888803 (-)
PWK/PhJ ENSLUMG00010035193
 protein coding gene ChrX:75976546-75998140 (-)
SPRET/EiJ ENSMSPG00010032105
 protein coding gene ChrX:80093851-80119072 (-)
WSB/EiJ ENSIUOG00005040582
 protein coding gene ChrX:77358825-77380445 (-)



Homology
more
  • Human Ortholog
    LAS1L, LAS1 like ribosome biogenesis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LAS1L, LAS1 like ribosome biogenesis factor
  • Synonyms
    dJ475B7.2, Las1, Las1-like, MRXSWTS, WTS
  • Links
    NCBI Gene ID: 81887
    UniProt: Q9Y4W2

  • Chr Location
    Xq12; chrX:65438549-65534818 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human LAS1L associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    77
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057421 Ensembl Gene Model | MGI Sequence Detail 21628 C57BL/6J ±  kb
transcript ENSMUST00000113864 Ensembl | MGI Sequence Detail 2581 Not Applicable  
polypeptide ENSMUSP00000109495 Ensembl | MGI Sequence Detail 776 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916404
References
more
  • Summaries
    All 32
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:381923 Giambruno R, et al., Affinity purification strategies for proteomic analysis of transcription factor complexes. J Proteome Res. 2013 Sep 6;12(9):4018-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory