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Las1l Gene Detail
Summary
  • Symbol
    Las1l
  • Name
    LAS1-like (S. cerevisiae)
  • Synonyms
    1810030A06Rik, 5830482G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923380
    NCBI Gene: 76130
  • Gene Overview
    MyGene.info: LAS1L
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:95935335-95956962 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 42.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923380
protein coding gene ChrX:95920045-95956974 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035922
protein coding gene ChrX:92286297-92309818 (-)
A/J MGP_AJ_G0035908
protein coding gene ChrX:92484197-92505173 (-)
AKR/J MGP_AKRJ_G0035824
protein coding gene ChrX:94923060-94949503 (-)
BALB/cJ MGP_BALBcJ_G0035891
protein coding gene ChrX:91208274-91241323 (-)
C3H/HeJ MGP_C3HHeJ_G0035599
protein coding gene ChrX:92780900-92802473 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036420
protein coding gene ChrX:95220320-95244351 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033249
protein coding gene ChrX:90488346-90508714 (-)
CAST/EiJ MGP_CASTEiJ_G0034886
protein coding gene ChrX:77288067-77311436 (-)
CBA/J MGP_CBAJ_G0035575
protein coding gene ChrX:98057643-98085542 (-)
DBA/2J MGP_DBA2J_G0035729
protein coding gene ChrX:91674623-91696473 (-)
FVB/NJ MGP_FVBNJ_G0035667
protein coding gene ChrX:91078554-91102887 (-)
LP/J MGP_LPJ_G0035819
protein coding gene ChrX:93306856-93330254 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035702
protein coding gene ChrX:102358991-102399835 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036447
protein coding gene ChrX:92026180-92047683 (-)
PWK/PhJ MGP_PWKPhJ_G0034585
protein coding gene ChrX:74957052-74978216 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034414
protein coding gene ChrX:78101540-78125875 (-)
WSB/EiJ MGP_WSBEiJ_G0035025
protein coding gene ChrX:90866557-90890782 (-)



Homology
more
  • Human Ortholog
    LAS1L, LAS1 like, ribosome biogenesis factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LAS1L, LAS1 like, ribosome biogenesis factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ475B7.2, Las1-like, WTS
  • Links
    NCBI Gene ID: 81887
    neXtProt AC: NX_Q9Y4W2
    UniProt: Q9Y4W2

  • Chr Location
    Xq12; chrX:65512582-65534806 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human LAS1L associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057421 Ensembl Gene Model | MGI Sequence Detail 21628 C57BL/6J ±  kb
transcript ENSMUST00000113864 Ensembl | MGI Sequence Detail 2581 Not Applicable  
polypeptide ENSMUSP00000109495 Ensembl | MGI Sequence Detail 776 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916404
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory