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Lpo Gene Detail
Summary
  • Symbol
    Lpo
  • Name
    lactoperoxidase
  • Synonyms
    5830499B15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923363
    NCBI Gene: 76113
  • Gene Overview
    MyGene.info: LPO
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:87806428-87826119 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 52.22 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    156 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923363
protein coding gene Chr11:87806428-87828289 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018913
protein coding gene Chr11:89440107-89461665 (-)
A/J MGP_AJ_G0018880
protein coding gene Chr11:85993137-86014368 (-)
AKR/J MGP_AKRJ_G0018850
protein coding gene Chr11:88566949-88588455 (-)
BALB/cJ MGP_BALBcJ_G0018853
protein coding gene Chr11:86394045-86416359 (-)
C3H/HeJ MGP_C3HHeJ_G0018667
protein coding gene Chr11:88610047-88632431 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019305
protein coding gene Chr11:92155800-92180812 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016938
protein coding gene Chr11:83019864-83042836 (-)
CAST/EiJ MGP_CASTEiJ_G0018222
protein coding gene Chr11:89306109-89329671 (-)
CBA/J MGP_CBAJ_G0018638
protein coding gene Chr11:96032015-96058122 (-)
DBA/2J MGP_DBA2J_G0018746
protein coding gene Chr11:85546420-85568606 (-)
FVB/NJ MGP_FVBNJ_G0018735
protein coding gene Chr11:85052563-85073950 (-)
LP/J MGP_LPJ_G0018816
protein coding gene Chr11:89932625-89953990 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018762
protein coding gene Chr11:96064034-96087212 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019345
protein coding gene Chr11:88805995-88832155 (-)
PWK/PhJ MGP_PWKPhJ_G0017992
protein coding gene Chr11:86396377-86419107 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017785
protein coding gene Chr11:88364860-88392588 (-)
WSB/EiJ MGP_WSBEiJ_G0018273
protein coding gene Chr11:88698046-88720554 (-)



Homology
more
  • Human Ortholog
    LPO, lactoperoxidase
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LPO, lactoperoxidase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SPO
  • Links
    NCBI Gene ID: 4025
    neXtProt AC: NX_P22079
    UniProt: P22079

  • Chr Location
    17q22; chr17:58238426-58268518 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76113 NCBI Gene Model | MGI Sequence Detail 19692 C57BL/6J ±  kb
    transcript NM_080420 RefSeq | MGI Sequence Detail 2927 C57BL/6  
    polypeptide NP_536345 RefSeq | MGI Sequence Detail 710 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR019791 Haem peroxidase, animal type
      IPR037120 Haem peroxidase domain superfamily, animal type
      IPR010255 Haem peroxidase superfamily
      IPR029587 Lactoperoxidase
    Molecular
    Reagents
    less
    • All nucleic 111
      cDNA 110
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 4
      Phenotypes 15
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    12/04/2018
    MGI 6.13
    The Jackson Laboratory