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Isy1 Gene Detail
Summary
  • Symbol
    Isy1
  • Name
    ISY1 splicing factor homolog
  • Synonyms
    5830446M03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923310
    NCBI Gene: 57905
Location & Maps
more
  • Sequence Map
    Chr6:87814269-87838798 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24530 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.13 cM, cytoband D2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ISY1, ISY1 splicing factor homolog
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ISY1, ISY1 splicing factor homolog
    Orthology source: HGNC
  • Synonyms
    FSAP33
  • Links
    NCBI Gene ID: 57461
    neXtProt AC: NX_Q9ULR0

  • Chr Location
    3q21.3; chr3:129127416-129161230 (-)  GRCh38.p2

  • Human Ortholog
    ISY1-RAB43, ISY1-RAB43 readthrough
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 100534599
    neXtProt AC: NX_Q9ULR0

  • Chr Location
    3q; chr3:129087569-129161230 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    11
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Isy1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057272 VEGA Gene Model | MGI Sequence Detail 24530 C57BL/6J ±  kb
transcript OTTMUST00000140968 VEGA | MGI Sequence Detail 5837 Not Applicable  
polypeptide OTTMUSP00000073738 VEGA | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    50 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000009121 pre-mRNA-splicing factor ISY1
  • PDB
  • InterPro Domains
    IPR009360 Isy1-like splicing
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
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MGI:1889387, MGI:2141605
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory