About   Help   FAQ
Ganc Gene Detail
Summary
  • Symbol
    Ganc
  • Name
    glucosidase, alpha; neutral C
  • Synonyms
    5830445O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923301
    NCBI Gene: 76051
  • Gene Overview
    MyGene.info: GANC
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120403896-120460866 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.31 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    442 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923301
protein coding gene Chr2:120403896-120461700 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026366
protein coding gene Chr2:123270732-123329498 (+)
A/J MGP_AJ_G0026327
protein coding gene Chr2:118217555-118276259 (+)
AKR/J MGP_AKRJ_G0026306
protein coding gene Chr2:121519204-121579756 (+)
BALB/cJ MGP_BALBcJ_G0026340
protein coding gene Chr2:118461503-118519105 (+)
C3H/HeJ MGP_C3HHeJ_G0026086
protein coding gene Chr2:121993422-122064376 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026787
protein coding gene Chr2:127282431-127345368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024167
protein coding gene Chr2:113238964-113296964 (+)
CAST/EiJ MGP_CASTEiJ_G0025548
protein coding gene Chr2:122305465-122369662 (+)
CBA/J MGP_CBAJ_G0026062
protein coding gene Chr2:131737470-131803261 (+)
DBA/2J MGP_DBA2J_G0026201
protein coding gene Chr2:117607753-117665369 (+)
FVB/NJ MGP_FVBNJ_G0026163
protein coding gene Chr2:116443636-116503590 (+)
LP/J MGP_LPJ_G0026302
protein coding gene Chr2:123526500-123588169 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026182
protein coding gene Chr2:136050415-136113809 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026842
protein coding gene Chr2:121644689-121706970 (+)
PWK/PhJ MGP_PWKPhJ_G0025284
protein coding gene Chr2:117210164-117272128 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025083
protein coding gene Chr2:120841004-120904006 (+)
WSB/EiJ MGP_WSBEiJ_G0025617
protein coding gene Chr2:122478815-122539351 (+)



Homology
more
  • Human Ortholog
    GANC, glucosidase alpha, neutral C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GANC, glucosidase alpha, neutral C
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2595
    neXtProt AC: NX_Q8TET4
    UniProt: Q8TET4

  • Chr Location
    15q15.1; chr15:42273658-42353666 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76051 NCBI Gene Model | MGI Sequence Detail 56971 C57BL/6J ±  kb
transcript NM_172672 RefSeq | MGI Sequence Detail 4818 C57BL/6  
polypeptide Q8BVW0 UniProt | EBI | MGI Sequence Detail 898 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR011013 Galactose mutarotase-like domain superfamily
    IPR000322 Glycoside hydrolase family 31
    IPR025887 Glycoside hydrolase family 31, N-terminal domain
    IPR017853 Glycoside hydrolase superfamily
    IPR013780 Glycosyl hydrolase, all-beta
    IPR030458 Glycosyl hydrolases family 31, active site
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory