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Ncapg2 Gene Detail
Summary
  • Symbol
    Ncapg2
  • Name
    non-SMC condensin II complex, subunit G2
  • Synonyms
    5830426I05Rik, Luzp5, mCAP-G2, Mtb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923294
    NCBI Gene: 76044
  • Gene Overview
    MyGene.info: NCAPG2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:116405355-116463532 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.65 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    781 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923294
protein coding gene Chr12:116405355-116463731 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020182
protein coding gene Chr12:119270520-119329490 (+)
A/J MGP_AJ_G0020138
protein coding gene Chr12:114917314-114971746 (+)
AKR/J MGP_AKRJ_G0020113
protein coding gene Chr12:118406990-118461441 (+)
BALB/cJ MGP_BALBcJ_G0020121
protein coding gene Chr12:115341922-115405254 (+)
C3H/HeJ MGP_C3HHeJ_G0019925
protein coding gene Chr12:118667629-118735888 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020568
protein coding gene Chr12:123042327-123106161 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018180
protein coding gene Chr12:111329635-111384925 (+)
CAST/EiJ MGP_CASTEiJ_G0019465
protein coding gene Chr12:112517051-112576068 (+)
CBA/J MGP_CBAJ_G0019892
protein coding gene Chr12:127922130-127983957 (+)
DBA/2J MGP_DBA2J_G0020009
protein coding gene Chr12:114279277-114334135 (+)
FVB/NJ MGP_FVBNJ_G0019994
protein coding gene Chr12:112973168-113032019 (+)
LP/J MGP_LPJ_G0020083
protein coding gene Chr12:119311503-119372075 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020030
protein coding gene Chr12:131230929-131297385 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020597
protein coding gene Chr12:117570504-117628938 (+)
PWK/PhJ MGP_PWKPhJ_G0019227
protein coding gene Chr12:109038122-109097513 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019032
protein coding gene Chr12:110513832-110572684 (+)
WSB/EiJ MGP_WSBEiJ_G0019523
protein coding gene Chr12:118525093-118583572 (+)



Homology
more
  • Human Ortholog
    NCAPG2, non-SMC condensin II complex subunit G2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NCAPG2, non-SMC condensin II complex subunit G2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAPG2, CAP-G2, hCAP-G2, LUZP5, MTB
  • Links
    NCBI Gene ID: 54892
    neXtProt AC: NX_Q86XI2
    UniProt: Q86XI2

  • Chr Location
    7q36.3; chr7:158631169-158704831 (-)  GRCh38.p7

Human Diseases
less
  • References
    16 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    257 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null embryos exhibit impaired inner cell mass expansion and die shortly after implantation and prior to gastrulation and blood cell development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76044 NCBI Gene Model | MGI Sequence Detail 58178 C57BL/6J ±  kb
    transcript NM_133762 RefSeq | MGI Sequence Detail 6571 C57BL/6  
    polypeptide Q6DFV1 UniProt | EBI | MGI Sequence Detail 1138 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 95
      cDNA 94
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 288
      Developmental Gene Expression 4
      Diseases 16
      Gene Ontology 6
      Phenotypes 257
    • Earliest
      J:37107 Mayford M, et al., Control of memory formation through regulated expression of a CaMKII transgene. Science. 1996 Dec 6;274(5293):1678-83
    • Latest
      J:265370 Kukreja L, et al., Differential Neurotoxicity Related to Tetracycline Transactivator and TDP-43 Expression in Conditional TDP-43 Mouse Model of Frontotemporal Lobar Degeneration. J Neurosci. 2018 Jul 4;38(27):6045-6062

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory