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Ncapg2 Gene Detail
Summary
  • Symbol
    Ncapg2
  • Name
    non-SMC condensin II complex, subunit G2
  • Synonyms
    5830426I05Rik, Luzp5, mCAP-G2, Mtb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923294
    NCBI Gene: 76044
  • Gene Overview
    MyGene.info: NCAPG2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:116405355-116463532 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      58178 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.65 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NCAPG2, non-SMC condensin II complex subunit G2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NCAPG2, non-SMC condensin II complex subunit G2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAPG2, CAP-G2, hCAP-G2, LUZP5, MTB
  • Links
    NCBI Gene ID: 54892
    neXtProt AC: NX_Q86XI2
    UniProt: Q86XI2

  • Chr Location
    7q36.3; chr7:158631169-158704831 (-)  GRCh38.p7

Human Diseases
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  • References
    16 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    235 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null embryos exhibit impaired inner cell mass expansion and die shortly after implantation and prior to gastrulation and blood cell development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76044 NCBI Gene Model | MGI Sequence Detail 58178 C57BL/6J ±  kb
    transcript NM_133762 RefSeq | MGI Sequence Detail 6604 C57BL/6  
    polypeptide Q6DFV1 UniProt | EBI | MGI Sequence Detail 1138 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      781 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 93
      cDNA 92
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 265
      Developmental Gene Expression 4
      Diseases 16
      Gene Ontology 6
      Phenotypes 235
    • Earliest
      J:37107 Mayford M, et al., Control of memory formation through regulated expression of a CaMKII transgene. Science. 1996 Dec 6;274(5293):1678-83
    • Latest
      J:261165 Wang X, et al., Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy. PLoS One. 2018;13(4):e0195486

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory