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Agmat
Gene Detail
Symbol

Name
ID
Agmat
agmatine ureohydrolase (agmatinase)
MGI:1923236
Synonyms
5033405N08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
74.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:141746672-141759263 bp, + strand
From VEGA annotation of GRCm38

  12592 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99855  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AGMAT
Protein SuperFamily: ureohydrolase/formiminoglutamase/proclavaminate amidino hydrolase
Gene Tree: Agmat

Human
homologs
AGMAT, agmatine ureohydrolase (agmatinase)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 79814
neXtProt AC: NX_Q9BSE5

Human Chr (Location): 1p36.21; chr1:15571699-15585110 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Genomic Mutations involving Agmat (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Agmat interacts with 32 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process putrescine biosynthetic process, spermidine biosynthetic process
Component extracellular exosome, mitochondrion
Function agmatinase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (10)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase agmat    NEW 
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000009931 (Evidence)
Ensembl Gene Model ENSMUSG00000040706 (Evidence)
Entrez Gene 75986 (Evidence)
UniGene 30032
DFCI TC1605845
DoTS DT.530279
NIA Mouse Gene Index U005050
EC 3.5.3.11
Consensus CDS Project CCDS38941.1
International Mouse Phenotyping Consortium Status Agmat
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009931 VEGA Gene Model | MGI Sequence Detail 12592 C57BL/6J ±  kb
transcript OTTMUST00000023069 VEGA | MGI Sequence Detail 1407 Not Applicable 
polypeptide OTTMUSP00000010524 VEGA | MGI Sequence Detail 358 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(194 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005925 Agmatinase-related
InterPro IPR006035 Ureohydrolase
InterPro IPR023696 Ureohydrolase domain
Protein Ontology PR:000003833 agmatinase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory