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Dock11
Gene Detail
Symbol

Name
ID
Dock11
dedicator of cytokinesis 11
MGI:1923224
Synonyms
5033414A21Rik, Zizimin2
Feature Type
protein coding gene
Genetic Map
Chromosome X
20.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:35888832-36076562 bp, + strand
From VEGA annotation of GRCm38

  187731 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:70950  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DOCK11
Gene Tree: Dock11

Human
homologs
DOCK11, dedicator of cytokinesis 11
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 139818
neXtProt AC: NX_Q5JSL3

Human Synonyms: ACG, bB128O4.1, ZIZ2

Human Chr (Location): Xq24; chrX:118495909-118686160 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Dock11 interacts with 198 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(40)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dock11    NEW 
Molecular
reagents
All nucleic(43) cDNA(43)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000017193 (Evidence)
Ensembl Gene Model ENSMUSG00000031093 (Evidence)
Entrez Gene 75974 (Evidence)
UniGene 32873
DFCI TC1582637, TC1591175
DoTS DT.530773, DT.87059686
NIA Mouse Gene Index U081915
Consensus CDS Project CCDS40923.1
International Mouse Phenotyping Consortium Status Dock11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017193 VEGA Gene Model | MGI Sequence Detail 187731 C57BL/6J ±  kb
transcript OTTMUST00000041633 VEGA | MGI Sequence Detail 6665 Not Applicable 
polypeptide OTTMUSP00000018699 VEGA | MGI Sequence Detail 2073 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(9) UniProt(3)
Polymorphisms
SNPs within 2kb(370 from dbSNP Build 137)    SNPs within 2kb including multiple locations(376)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR026791 Dedicator of cytokinesis
InterPro IPR021816 Dedicator of cytokinesis C/D, N-terminal
InterPro IPR010703 Dedicator of cytokinesis C-terminal
InterPro IPR027007 DHR-1 domain
InterPro IPR027357 DHR-2 domain
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Protein Ontology PR:000006618 dedicator of cytokinesis protein 11
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory