Tmem56 Gene Detail

Summary

• Symbol
  Tmem56
• Name
  transmembrane protein 56
• Synonyms
  4930577M16Rik, C730036B01Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1923195
  NCBI Gene: 99887

Location & Maps

• Sequence Map
  Chr3:121201761-121283098 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    81338 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 52.94 cM, cytoband G3
• Mapping Data
  3 experiments

Homology

• Human Ortholog
  TMEM56, transmembrane protein 56

• Vertebrate Orthologs
  9

• Human Ortholog
  TMEM56, transmembrane protein 56
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:26477

  NCBI Gene ID: 148534

  neXtProt AC: NX_Q96MV1

  UniProt: Q96MV1

  
  
• Chr Location
  1p21.3; chr1:95092517-95197607 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 45107
  1 human;1 mouse;1 rat;1 chimpanzee;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMEM56
• Gene Tree
  Tmem56
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (other)
  1
• Gene trapped
  2
• Radiation induced
  1
• Targeted
  4
• Genomic Mutations
  2 involving Tmem56
• Find Mice (IMSR)
  12 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  2

• External Resources
  FuncBase

Expression

• Assay Results
  42
• Tissues
  19
• cDNA Data
  13
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN tmem56b

Interactions

• Tmem56 interacts with 392 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

Sequences &
Gene Models

• All Sequences
  62
• RefSeq
  16
• UniProt
  2
• CCDS
  CCDS17800.1

• VEGA
  OTTMUSG00000032849 (Evidence)
• Ensembl
  ENSMUSG00000028132 (Evidence)
• NCBI Gene
  99887

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000032849	VEGA Gene Model | MGI Sequence Detail	81338	C57BL/6J
transcript	OTTMUST00000081849	VEGA | MGI Sequence Detail	6696	Not Applicable
polypeptide	OTTMUSP00000043838	VEGA | MGI Sequence Detail	276	Not Applicable

Polymorphisms

• SNPs within 2kb
  778 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000030662 transmembrane protein 56
  (term hierarchy)
• InterPro Domains
  IPR006634 TRAM/LAG1/CLN8 homology domain

Molecular
Reagents

• All nucleic 14

  cDNA 13

  Primer pair 1

  
  

  Microarray probesets 9

Other
Accession IDs

MGI:2139869, MGI:2139968

References

• Summaries
  All 38

  Developmental Gene Expression 3

  Diseases 1

  Gene Ontology 2

  Phenotypes 9
• Earliest
  J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582