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Tcam1 Gene Detail
Summary
  • Symbol
    Tcam1
  • Name
    testicular cell adhesion molecule 1
  • Synonyms
    4930570F09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923120
    NCBI Gene: 75870
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106276672-106288745 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923120
protein coding gene Chr11:106273088-106288745 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019302
protein coding gene Chr11:109566712-109580271 (+)
A/J MGP_AJ_G0019270
protein coding gene Chr11:104903527-104915540 (+)
AKR/J MGP_AKRJ_G0019239
protein coding gene Chr11:108030898-108042970 (+)
BALB/cJ MGP_BALBcJ_G0019244
protein coding gene Chr11:105312269-105324340 (+)
C3H/HeJ MGP_C3HHeJ_G0019053
protein coding gene Chr11:108320431-108332729 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019694
protein coding gene Chr11:112916236-112929795 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017318
protein coding gene Chr11:102181092-102193686 (+)
CAST/EiJ MGP_CASTEiJ_G0018606
protein coding gene Chr11:109376410-109393133 (+)
CBA/J MGP_CBAJ_G0019022
protein coding gene Chr11:117616332-117628425 (+)
DBA/2J MGP_DBA2J_G0019134
protein coding gene Chr11:104371563-104383648 (+)
FVB/NJ MGP_FVBNJ_G0019125
protein coding gene Chr11:103875483-103887648 (+)
LP/J MGP_LPJ_G0019204
protein coding gene Chr11:110010468-110023360 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019155
protein coding gene Chr11:116900585-116914671 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019731
protein coding gene Chr11:108525136-108538113 (+)
PWK/PhJ MGP_PWKPhJ_G0018371
protein coding gene Chr11:105469144-105484294 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018162
protein coding gene Chr11:108286053-108303884 (+)
WSB/EiJ MGP_WSBEiJ_G0018657
protein coding gene Chr11:108482863-108497780 (+)



Homology
more
  • Human Ortholog
    TCAM1P, testicular cell adhesion molecule 1, pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    TCAM1P, testicular cell adhesion molecule 1, pseudogene
    Orthology source: HGNC
  • Synonyms
    TCAM1
  • Links
    NCBI Gene ID: 146771

  • Chr Location
    17q23.3; chr17:63857016-63864379 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020712 Ensembl Gene Model | MGI Sequence Detail 12074 C57BL/6J ±  kb
    transcript ENSMUST00000044462 Ensembl | MGI Sequence Detail 3511 Not Applicable  
    polypeptide ENSMUSP00000044757 Ensembl | MGI Sequence Detail 548 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR013768 Intercellular adhesion molecule, N-terminal
      IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144159
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:66483 Sakatani S, et al., Structure, expression, and conserved physical linkage of mouse testicular cell adhesion molecule-1 (TCAM-1) gene. Genome. 2000 Dec;43(6):957-62
    • Latest
      J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/05/2019
    MGI 6.14
    The Jackson Laboratory