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Arl5b Gene Detail
Summary
  • Symbol
    Arl5b
  • Name
    ADP-ribosylation factor-like 5B
  • Synonyms
    4930587A11Rik, Arl8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923119
    NCBI Gene: 75869
Location & Maps
more
  • Sequence Map
    Chr2:15049395-15082456 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33062 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 10.98 cM, cytoband A2
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ARL5B, ADP ribosylation factor like GTPase 5B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARL5B, ADP ribosylation factor like GTPase 5B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ARL8
  • Links
    NCBI Gene ID: 221079
    neXtProt AC: NX_Q96KC2

  • Chr Location
    10p12.31; chr10:18659335-18681639 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    25
  • Gene trapped
    23
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011387 VEGA Gene Model | MGI Sequence Detail 33062 C57BL/6J ±  kb
transcript OTTMUST00000026651 VEGA | MGI Sequence Detail 6981 Not Applicable  
polypeptide OTTMUSP00000012180 VEGA | MGI Sequence Detail 180 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    81 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004289 ADP-ribosylation factor-like protein 5B
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR006689 Small GTPase superfamily, ARF/SAR type
    IPR024156 Small GTPase superfamily, ARF type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 87
    cDNA 87

    Microarray probesets 4
Other
Accession IDs
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MGI:2139323
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218760 Kitai Y, et al., Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015 Jan 9;290(2):1269-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory