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Arl5b Gene Detail
Summary
  • Symbol
    Arl5b
  • Name
    ADP-ribosylation factor-like 5B
  • Synonyms
    4930587A11Rik, Arl8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923119
    NCBI Gene: 75869
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:15055362-15082456 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 10.98 cM, cytoband A2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923119
protein coding gene Chr2:15049395-15082456 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025366
protein coding gene Chr2:12600906-12633958 (+)
A/J MGP_AJ_G0025344
protein coding gene Chr2:12128512-12161905 (+)
AKR/J MGP_AKRJ_G0025312
protein coding gene Chr2:12487961-12521016 (+)
BALB/cJ MGP_BALBcJ_G0025339
protein coding gene Chr2:12133577-12166622 (+)
C3H/HeJ MGP_C3HHeJ_G0025099
protein coding gene Chr2:12454986-12490409 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025781
protein coding gene Chr2:12897835-12930925 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023197
protein coding gene Chr2:11638579-11672036 (+)
CAST/EiJ MGP_CASTEiJ_G0024562
protein coding gene Chr2:12431032-12464150 (+)
CBA/J MGP_CBAJ_G0025078
protein coding gene Chr2:13507175-13540325 (+)
DBA/2J MGP_DBA2J_G0025210
protein coding gene Chr2:12033651-12067281 (+)
FVB/NJ MGP_FVBNJ_G0025172
protein coding gene Chr2:11899330-11932391 (+)
LP/J MGP_LPJ_G0025296
protein coding gene Chr2:12500794-12535172 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025204
protein coding gene Chr2:13329224-13363832 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025840
protein coding gene Chr2:12403616-12436663 (+)
PWK/PhJ MGP_PWKPhJ_G0024313
protein coding gene Chr2:11876032-11909549 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024113
protein coding gene Chr2:12497547-12530561 (+)
WSB/EiJ MGP_WSBEiJ_G0024632
protein coding gene Chr2:12539324-12572361 (+)



Homology
more
  • Human Ortholog
    ARL5B, ADP ribosylation factor like GTPase 5B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARL5B, ADP ribosylation factor like GTPase 5B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARL8
  • Links
    NCBI Gene ID: 221079
    neXtProt AC: NX_Q96KC2
    UniProt: Q96KC2

  • Chr Location
    10p12.31; chr10:18659335-18681639 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75869 NCBI Gene Model | MGI Sequence Detail 27095 C57BL/6J ±  kb
transcript NM_029466 RefSeq | MGI Sequence Detail 6901 C57BL/6  
polypeptide Q9D4P0 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    cDNA 88

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139323
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218760 Kitai Y, et al., Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015 Jan 9;290(2):1269-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory