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Tasp1
Gene Detail
Symbol

Name
ID
Tasp1
taspase, threonine aspartase 1
MGI:1923062
Synonyms
4930485D02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
69.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:139833480-140066805 bp, - strand
From VEGA annotation of GRCm38

  233326 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9795  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tasp1

Human
homologs
Human Homolog TASP1, taspase, threonine aspartase, 1
NCBI Gene ID 55617
neXtProt AC  NX_Q9H6P5
Human Synonyms  C20orf13, dJ585I14.2
Human Chr (Location)  20p12.1; chr20:13389389-13638936 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(15) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display prenatal and early postnatal lethality, reduced body size, impaired suckling behavior, homeotic transformations of the axial skeleton, and cell cycle defects.
 
Interactions
Tasp1 interacts with 219 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process positive regulation of transcription, DNA-templated, proteolysis
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) cDNA(30)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015577 (Evidence)
Ensembl Gene ModelENSMUSG00000039033 (Evidence)
Entrez Gene75812 (Evidence)
UniGene293449
DFCITC1585343, TC1582027, TC1775900, TC1682311, TC1773686
DoTSDT.101190364, DT.91580920, DT.87035918, DT.101227560, DT.55243518, DT.485784, DT.101363007, DT.97409424
NIA Mouse Gene IndexU023417
EC3.4.25.-
Consensus CDS ProjectCCDS16802.1, CCDS50731.1
International Mouse Knockout Project StatusTasp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015577 VEGA Gene Model | MGI Sequence Detail 233326 C57BL/6J ±  kb
transcript OTTMUST00000037007 VEGA | MGI Sequence Detail 2258 Not Applicable 
polypeptide OTTMUSP00000016604 VEGA | MGI Sequence Detail 420 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(17) UniProt(3)
Polymorphisms
SNPs within 2kb(1619 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1625)
Protein-related
information
ResourceIDDescription
InterPro IPR000246 Peptidase T2, asparaginase 2
Protein Ontology PR:000016088 threonine aspartase 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205038 Oyama T, et al., Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. Dev Cell. 2013 Oct 28;27(2):188-200
All references(36)
Other
accession IDs
MGI:2139420

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory