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Rab11fip1 Gene Detail
Summary
  • Symbol
    Rab11fip1
  • Name
    RAB11 family interacting protein 1 (class I)
  • Synonyms
    2010200K21Rik, 4833414G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923017
    NCBI Gene: 75767
  • Gene Overview
    MyGene.info: RAB11FIP1
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:27138773-27174646 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 15.91 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923017
protein coding gene Chr8:27138773-27174646 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033503
protein coding gene Chr8:25326363-25363158 (-)
A/J MGP_AJ_G0033483
protein coding gene Chr8:24358268-24394954 (-)
AKR/J MGP_AKRJ_G0033408
protein coding gene Chr8:25162072-25207899 (-)
BALB/cJ MGP_BALBcJ_G0033479
protein coding gene Chr8:24517313-24555476 (-)
C3H/HeJ MGP_C3HHeJ_G0033193
protein coding gene Chr8:25385530-25421479 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033995
protein coding gene Chr8:26306352-26342824 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030945
protein coding gene Chr8:21608795-21644616 (-)
CAST/EiJ MGP_CASTEiJ_G0032519
protein coding gene Chr8:24870504-24911987 (-)
CBA/J MGP_CBAJ_G0033168
protein coding gene Chr8:27343884-27388767 (-)
DBA/2J MGP_DBA2J_G0033323
protein coding gene Chr8:24324694-24361206 (-)
FVB/NJ MGP_FVBNJ_G0033267
protein coding gene Chr8:24138146-24174792 (-)
LP/J MGP_LPJ_G0033412
protein coding gene Chr8:25282722-25321852 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033310
protein coding gene Chr8:26785341-26827607 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034014
protein coding gene Chr8:25147549-25186743 (-)
PWK/PhJ MGP_PWKPhJ_G0032230
protein coding gene Chr8:23989277-24025509 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032064
protein coding gene Chr8:24531389-24573110 (-)
WSB/EiJ MGP_WSBEiJ_G0032635
protein coding gene Chr8:25331133-25375240 (-)



Homology
more
  • Human Ortholog
    RAB11FIP1, RAB11 family interacting protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB11FIP1, RAB11 family interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NOEL1A, rab11-FIP1, RCP
  • Links
    NCBI Gene ID: 80223
    neXtProt AC: NX_Q6WKZ4
    UniProt: Q6WKZ4

  • Chr Location
    8p11.23; chr8:37858947-37899516 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    6 phenotype references
Homozygous knockout results in reduced metastatic potential of pancreatic adenocarcinoma (PDAC) tumor cells in KPC (PDAC model) mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75767 NCBI Gene Model | MGI Sequence Detail 35874 C57BL/6J ±  kb
transcript NM_001080813 RefSeq | MGI Sequence Detail 7965 C57BL/6  
polypeptide Q9D620 UniProt | EBI | MGI Sequence Detail 645 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917512
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244261 Gundry C, et al., Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion. Nat Commun. 2017 Mar 15;8:14646

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory