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Aftph Gene Detail
Summary
  • Symbol
    Aftph
  • Name
    aftiphilin
  • Synonyms
    9130023F12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923012
    NCBI Gene: 216549
  • Gene Overview
    MyGene.info: AFTPH
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:20685084-20741556 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 13.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923012
protein coding gene Chr11:20685084-20741589 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018068
protein coding gene Chr11:18237380-18297708 (-)
A/J MGP_AJ_G0018041
protein coding gene Chr11:17606302-17662478 (-)
AKR/J MGP_AKRJ_G0018005
protein coding gene Chr11:18237986-18295799 (-)
BALB/cJ MGP_BALBcJ_G0018009
protein coding gene Chr11:17727529-17784393 (-)
C3H/HeJ MGP_C3HHeJ_G0017823
protein coding gene Chr11:18129537-18188361 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018461
protein coding gene Chr11:19074022-19138209 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016119
protein coding gene Chr11:16579575-16637703 (-)
CAST/EiJ MGP_CASTEiJ_G0017384
protein coding gene Chr11:18102555-18162808 (-)
CBA/J MGP_CBAJ_G0017797
protein coding gene Chr11:19897436-19961235 (-)
DBA/2J MGP_DBA2J_G0017907
protein coding gene Chr11:17559616-17616191 (-)
FVB/NJ MGP_FVBNJ_G0017899
protein coding gene Chr11:17302908-17360853 (-)
LP/J MGP_LPJ_G0017978
protein coding gene Chr11:18399055-18457424 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017925
protein coding gene Chr11:20325170-20386526 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018502
protein coding gene Chr11:18308782-18365817 (-)
PWK/PhJ MGP_PWKPhJ_G0017164
protein coding gene Chr11:17576751-17633989 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016962
protein coding gene Chr11:18051078-18111799 (-)
WSB/EiJ MGP_WSBEiJ_G0017438
protein coding gene Chr11:17960487-18020399 (-)



Homology
more
  • Human Ortholog
    AFTPH, aftiphilin
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AFTPH, aftiphilin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Nbla10388
  • Links
    NCBI Gene ID: 54812
    neXtProt AC: NX_Q6ULP2
    UniProt: Q6ULP2

  • Chr Location
    2p14; chr2:64524305-64593005 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216549 NCBI Gene Model | MGI Sequence Detail 56473 C57BL/6J ±  kb
transcript NM_001290545 RefSeq | MGI Sequence Detail 4065 C57BL/6  
polypeptide Q80WT5 UniProt | EBI | MGI Sequence Detail 931 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144368, MGI:2144378, MGI:2144382, MGI:2144387, MGI:2144439
References
more
  • Summaries
    All 36
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory