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Bcl2l12 Gene Detail
Summary
  • Symbol
    Bcl2l12
  • Name
    BCL2-like 12 (proline rich)
  • Synonyms
    2810475P17Rik, 5430429M05Rik, Bcl2-L12, Bcl-L12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922986
    NCBI Gene: 75736
  • Gene Overview
    MyGene.info: BCL2L12
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr7:44991222-44998712 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7491 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.07 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    BCL2L12, BCL2 like 12
  • Vertebrate Orthologs
    6
  • Human Ortholog
    BCL2L12, BCL2 like 12
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 83596
    neXtProt AC: NX_Q9HB09
    UniProt: Q9HB09

  • Chr Location
    19q13.33; chr19:49665072-49673916 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    152 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023474 VEGA Gene Model | MGI Sequence Detail 7491 C57BL/6J ±  kb
transcript OTTMUST00000057113 VEGA | MGI Sequence Detail 1075 Not Applicable  
polypeptide OTTMUSP00000027515 VEGA | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    89 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920050
References
more
  • Summaries
    All 174
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 152
  • Earliest
    J:98127 Sato M, et al., Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity. 2000 Oct;13(4):539-48
  • Latest
    J:264199 Webster B, et al., Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses. Elife. 2018 Jun 19;7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory