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Mff
Gene Detail
Symbol

Name
ID
Mff
mitochondrial fission factor
MGI:1922984
Synonyms
5230400G24Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
42.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:82724890-82752394 bp, + strand
From VEGA annotation of GRCm38

  27505 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:87000  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MFF
Gene Tree: Mff

Human
homologs
MFF, mitochondrial fission factor
Orthology source: HGNC

IDs:
NCBI Gene ID: 56947
neXtProt AC: NX_Q9GZY8

Human Synonyms: C2orf33, GL004

Human Chr (Location): 2q36.3; chr2:227325151-227357836 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mff interacts with 152 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process mitochondrial fission, mitochondrion morphogenesis
Component cell junction, cytoplasmic vesicle, ...
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mff ; ZFIN mff    NEW 
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000034764 (Evidence)
Ensembl Gene Model ENSMUSG00000026150 (Evidence)
Entrez Gene 75734 (Evidence)
DFCI TC1706969, TC1589109, TC1585210, TC1572269
DoTS DT.101397215, DT.110889529, DT.110889490, DT.110889533, DT.87026036, DT.495515, DT.91289740
NIA Mouse Gene Index U000499
Consensus CDS Project CCDS15098.1
International Mouse Phenotyping Consortium Status Mff
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034764 VEGA Gene Model | MGI Sequence Detail 27505 C57BL/6J ±  kb
transcript OTTMUST00000088345 VEGA | MGI Sequence Detail 2087 Not Applicable 
polypeptide OTTMUSP00000048133 VEGA | MGI Sequence Detail 316 Not Applicable 

For the selected sequences
All sequences(152) RefSeq(36) UniProt(7)
Polymorphisms
SNPs within 2kb(284 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008518 FATE/Miff/Tango-11
Protein Ontology PR:000010366 mitochondrial fission factor
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:200469 Loson OC, et al., Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell. 2013 Mar;24(5):659-67
All references(30)
Other
accession IDs
MGI:2138195

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory