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Fam227a Gene Detail
Summary
  • Symbol
    Fam227a
  • Name
    family with sequence similarity 227, member A
  • Synonyms
    4933432B09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922979
    NCBI Gene: 75729
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79609576-79658956 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.81 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    216 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922979
protein coding gene Chr15:79609576-79658956 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022079
protein coding gene Chr15:79897791-79956593 (-)
A/J MGP_AJ_G0022040
protein coding gene Chr15:77134232-77187848 (-)
AKR/J MGP_AKRJ_G0022015
protein coding gene Chr15:79293083-79345773 (-)
BALB/cJ MGP_BALBcJ_G0022046
protein coding gene Chr15:77154206-77203479 (-)
C3H/HeJ MGP_C3HHeJ_G0021817
protein coding gene Chr15:79284598-79336423 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022489
protein coding gene Chr15:83043263-83096604 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020019
protein coding gene Chr15:73614289-73663465 (-)
CAST/EiJ MGP_CASTEiJ_G0021338
protein coding gene Chr15:79991960-80044330 (-)
CBA/J MGP_CBAJ_G0021782
protein coding gene Chr15:85627912-85679601 (-)
DBA/2J MGP_DBA2J_G0021911
protein coding gene Chr15:76625690-76675551 (-)
FVB/NJ MGP_FVBNJ_G0021889
protein coding gene Chr15:75650242-75700572 (-)
LP/J MGP_LPJ_G0021979
protein coding gene Chr15:80083956-80143800 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021909
protein coding gene Chr15:90727679-90780944 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022503
protein coding gene Chr15:79309648-79366992 (-)
PWK/PhJ MGP_PWKPhJ_G0021080
protein coding gene Chr15:76635032-76685915 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020917
protein coding gene Chr15:79118000-79166930 (-)
WSB/EiJ MGP_WSBEiJ_G0021390
protein coding gene Chr15:79694769-79753979 (-)



Homology
more
  • Human Ortholog
    FAM227A, family with sequence similarity 227 member A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FAM227A, family with sequence similarity 227 member A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 646851
    neXtProt AC: NX_F5H4B4
    UniProt: F5H4B4

  • Chr Location
    22q13.1; chr22:38578120-38656629 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Fam227a
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75729 NCBI Gene Model | MGI Sequence Detail 49381 C57BL/6J ±  kb
transcript NM_029407 RefSeq | MGI Sequence Detail 5187 C57BL/6  
polypeptide NP_083683 RefSeq | MGI Sequence Detail 625 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR029417 FAM227 Protein
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 41
    Diseases 1
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/20/2020
MGI 6.16
The Jackson Laboratory