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Cul5 Gene Detail
Summary
  • Symbol
    Cul5
  • Name
    cullin 5
  • Synonyms
    4921514I20Rik, 8430423K24Rik, C030032G03Rik, C330021I08Rik, VACM-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922967
    NCBI Gene: 75717
  • Gene Overview
    MyGene.info: CUL5
Location & Maps
more
  • Sequence Map
    Chr9:53614582-53670014 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      55433 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 29.12 cM, cytoband C
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CUL5, cullin 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CUL5, cullin 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    VACM1, VACM-1
  • Links
    NCBI Gene ID: 8065
    neXtProt AC: NX_Q93034

  • Chr Location
    11q22.3; chr11:108008682-108107766 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2597
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CUL5
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030717 VEGA Gene Model | MGI Sequence Detail 55433 C57BL/6J ±  kb
transcript OTTMUST00000076035 VEGA | MGI Sequence Detail 3585 Not Applicable  
polypeptide OTTMUSP00000039960 VEGA | MGI Sequence Detail 855 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 8
Other
Accession IDs
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MGI:1918729, MGI:1924813, MGI:1925779, MGI:2143157
References
more
  • Summaries
    All 46
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:38757 Byrd PJ, et al., Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23 [letter]. Genome Res. 1997 Jan;7(1):71-5
  • Latest
    J:232899 Moon UY, et al., Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory