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Rbm12 Gene Detail
Summary
  • Symbol
    Rbm12
  • Name
    RNA binding motif protein 12
  • Synonyms
    5730420G12Rik, 9430070C08Rik, MGC:30712, MGC:38279, SWAN
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922960
    NCBI Gene: 75710
  • Gene Overview
    MyGene.info: RBM12
Location & Maps
more
  • Sequence Map
    Chr2:156091958-156111978 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20021 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 77.35 cM, cytoband H2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RBM12, RNA binding motif protein 12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    RBM12, RNA binding motif protein 12
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HRIHFB2091, SWAN
  • Links
    NCBI Gene ID: 10137
    neXtProt AC: NX_Q9NTZ6

  • Chr Location
    20q11.21; chr20:35648925-35664956 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 34993
    1 human;1 mouse;2 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: RBM12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Chemically induced (ENU)
    1
  • Targeted
    1
  • Incidental Mutations
Mice homozygous for an ENU mutation exhibit open neural tube and embryonic growth retardation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016088 VEGA Gene Model | MGI Sequence Detail 20021 C57BL/6J ±  kb
transcript OTTMUST00000038405 VEGA | MGI Sequence Detail 6667 Not Applicable  
polypeptide OTTMUSP00000017204 VEGA | MGI Sequence Detail 992 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    87 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013784 RNA-binding protein 12
  • PDB
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGI:1924605, MGI:2139092
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:186861 Sun M, et al., Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse. G3 (Bethesda). 2012 Jan;2(1):143-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory