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Prpf6
Gene Detail
Symbol

Name
ID
Prpf6
PRP6 pre-mRNA splicing factor 6 homolog (yeast)
MGI:1922946
Synonyms
1190003A07Rik, 2610031L17Rik, ANT-1, MGC:11655, MGC:36967, MGC:38351, U5-102K
Feature Type
protein coding gene
Genetic Map
Chromosome 2
103.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:181591868-181655651 bp, + strand
From VEGA annotation of GRCm38

  63784 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5368  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Prpf6

Human
homologs
Human Homolog PRPF6, pre-mRNA processing factor 6
NCBI Gene ID 24148
neXtProt AC  NX_O94906
Human Synonyms  ANT1, ANT-1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K
Human Chr (Location)  20q13.33; chr20:63981064-64033100 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PRPF6
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(19) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prpf6 interacts with 38 markers (Mir7-1, Mir7-2, Mir135a-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process mRNA processing, mRNA splicing, via spliceosome, ...
Component catalytic step 2 spliceosome, intracellular, ...
Function androgen receptor binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (22)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
RT-PCR 2
cDNA source data(190)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(191) cDNA(190) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016808 (Evidence)
Ensembl Gene ModelENSMUSG00000002455 (Evidence)
Entrez Gene68879 (Evidence)
UniGene292001
DFCITC1594267, TC1572305
DoTSDT.97382159, DT.490398, DT.101737842
NIA Mouse Gene IndexU002989
Consensus CDS ProjectCCDS38381.1
International Mouse Knockout Project StatusPrpf6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016808 VEGA Gene Model | MGI Sequence Detail 63784 C57BL/6J ±  kb
transcript OTTMUST00000040822 VEGA | MGI Sequence Detail 3048 Not Applicable 
polypeptide OTTMUSP00000018255 VEGA | MGI Sequence Detail 941 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(207 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010491 PRP1 splicing factor, N-terminal
InterPro IPR003107 RNA-processing protein, HAT helix
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
Protein Ontology PR:000013287 pre-mRNA-processing factor 6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(35)
Other
accession IDs
MGI:1916129

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory