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Lin37 Gene Detail
Summary
  • Symbol
    Lin37
  • Name
    lin-37 homolog (C. elegans)
  • Synonyms
    1810054G18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922910
    NCBI Gene: 75660
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30555441-30559723 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 18.58 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922910
protein coding gene Chr7:30555441-30559838 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032027
protein coding gene Chr7:29560476-29564873 (-)
A/J MGP_AJ_G0032004
protein coding gene Chr7:28760371-28764768 (-)
AKR/J MGP_AKRJ_G0031937
protein coding gene Chr7:29492091-29496488 (-)
BALB/cJ MGP_BALBcJ_G0032011
protein coding gene Chr7:28941878-28946275 (-)
C3H/HeJ MGP_C3HHeJ_G0031730
protein coding gene Chr7:29948305-29952702 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032477
protein coding gene Chr7:30518326-30529096 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029527
protein coding gene Chr7:29787696-29792313 (-)
CAST/EiJ MGP_CASTEiJ_G0031064
protein coding gene Chr7:23203765-23208145 (-)
CBA/J MGP_CBAJ_G0031696
protein coding gene Chr7:31971944-31976341 (-)
DBA/2J MGP_DBA2J_G0031848
protein coding gene Chr7:28489258-28493638 (-)
FVB/NJ MGP_FVBNJ_G0031805
protein coding gene Chr7:28620445-28624842 (-)
LP/J MGP_LPJ_G0031929
protein coding gene Chr7:29870388-29874768 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031841
protein coding gene Chr7:31213411-31217808 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032505
protein coding gene Chr7:29001519-29005915 (-)
PWK/PhJ MGP_PWKPhJ_G0027017
protein coding gene Chr4:37010386-37016532 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030623
protein coding gene Chr7:20010906-20015283 (-)
WSB/EiJ MGP_WSBEiJ_G0031174
protein coding gene Chr7:29387768-29392451 (-)



Homology
more
  • Human Ortholog
    LIN37, lin-37 DREAM MuvB core complex component
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LIN37, lin-37 DREAM MuvB core complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    F25965, lin-37, ZK418.4
  • Links
    NCBI Gene ID: 55957
    neXtProt AC: NX_Q96GY3
    UniProt: Q96GY3

  • Chr Location
    19q13.12; chr19:35748361-35754519 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75660 NCBI Gene Model | MGI Sequence Detail 4283 C57BL/6J ±  kb
transcript NM_001290569 RefSeq | MGI Sequence Detail 1124 C57BL/6  
polypeptide Q9D8N6 UniProt | EBI | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:247509 Mages CF, et al., The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence. Elife. 2017 Sep 18;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory