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Pabpc1l
Gene Detail
Symbol

Name
ID
Pabpc1l
poly(A) binding protein, cytoplasmic 1-like
MGI:1922908
Synonyms
1810053B01Rik, ePAB
Feature Type
protein coding gene
Genetic Map
Chromosome 2
84.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:164025450-164050538 bp, + strand
From VEGA annotation of GRCm38

  25089 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77989  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pabpc1l

Human
homologs
Human Homolog PABPC1L, poly(A) binding protein, cytoplasmic 1-like
NCBI Gene ID 80336
neXtProt AC  NX_Q4VXU2
Human Synonyms  C20orf119, dJ1069P2.3, ePAB, PABPC1L1
Human Chr (Location)  chr20:44910060-44958944 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit impaired oocyte maturation and female infertility.
 
Interactions
Pabpc1l interacts with 84 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process mRNA polyadenylation, oocyte maturation
Component extracellular vesicular exosome
Function molecular_function
Expression
Literature Summary: (1 records)
Data Summary: Results (27)    Tissues (18)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 4
RT-PCR 23
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016137 (Evidence)
Ensembl Gene ModelENSMUSG00000054582 (Evidence)
Entrez Gene381404 (Evidence)
UniGene82301
DFCITC1607233
DoTSDT.50314892
NIA Mouse Gene IndexU002795
Consensus CDS ProjectCCDS50792.1
International Mouse Knockout Project StatusPabpc1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016137 VEGA Gene Model | MGI Sequence Detail 25089 C57BL/6J ±  kb
transcript OTTMUST00000038590 VEGA | MGI Sequence Detail 2354 Not Applicable 
polypeptide OTTMUSP00000017274 VEGA | MGI Sequence Detail 607 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(13) UniProt(4)
Polymorphisms
SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4
InterPro IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000012205 polyadenylate-binding protein 1-like
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:210253 Ozturk S, et al., Epab is dispensable for mouse spermatogenesis and male fertility. Mol Reprod Dev. 2014 May;81(5):390
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory