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Ssmem1 Gene Detail
Summary
  • Symbol
    Ssmem1
  • Name
    serine-rich single-pass membrane protein 1
  • Synonyms
    1700016K02Rik, 1700025E21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922897
    NCBI Gene: 75647
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:30509848-30520253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 12.52 cM, cytoband A3.3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922897
 protein coding gene Chr6:30509790-30520253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030538
 protein coding gene Chr6:28398856-28411459 (+)
A/J MGP_AJ_G0030511
 protein coding gene Chr6:27178085-27188504 (+)
AKR/J MGP_AKRJ_G0030438
 protein coding gene Chr6:28087901-28098288 (+)
BALB/cJ MGP_BALBcJ_G0030521
 protein coding gene Chr6:27328573-27338968 (+)
C3H/HeJ MGP_C3HHeJ_G0030234
 protein coding gene Chr6:28080703-28091095 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030975
 protein coding gene Chr6:29204172-29214579 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028186
 protein coding gene Chr6:25373992-25384309 (+)
CAST/EiJ MGP_CASTEiJ_G0029636
 protein coding gene Chr6:27903118-27913496 (+)
CBA/J MGP_CBAJ_G0030212
 protein coding gene Chr6:30316683-30327188 (+)
DBA/2J MGP_DBA2J_G0030356
 protein coding gene Chr6:27106264-27116951 (+)
FVB/NJ MGP_FVBNJ_G0030310
 protein coding gene Chr6:26873344-26883755 (+)
LP/J MGP_LPJ_G0030443
 protein coding gene Chr6:28536276-28546679 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030346
 protein coding gene Chr6:32757645-32768021 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031005
 protein coding gene Chr6:27961139-27972542 (+)
PWK/PhJ MGP_PWKPhJ_G0029350
 protein coding gene Chr6:26684124-26694881 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029186
 protein coding gene Chr6:27704353-27714819 (+)
WSB/EiJ MGP_WSBEiJ_G0029712
 protein coding gene Chr6:27930748-27941936 (+)



Homology
more
  • Human Ortholog
    SSMEM1, serine rich single-pass membrane protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SSMEM1, serine rich single-pass membrane protein 1
  • Synonyms
    C7orf45
  • Links
    NCBI Gene ID: 136263
    neXtProt AC: NX_Q8WWF3
    UniProt: Q8WWF3

  • Chr Location
    7q32.2; chr7:130205410-130216844 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029784 Ensembl Gene Model | MGI Sequence Detail 10406 C57BL/6J ±  kb
    transcript ENSMUST00000031798 Ensembl | MGI Sequence Detail 1155 Not Applicable  
    polypeptide ENSMUSP00000031798 Ensembl | MGI Sequence Detail 244 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR027955 Protein of unknown function DUF4636
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1916656
    References
    more
    • Summaries
      All 24
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:296963 Nozawa K, et al., Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice. Biol Reprod. 2020 Aug 4;103(2):244-253
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory