About   Help   FAQ
Metap1 Gene Detail
Summary
  • Symbol
    Metap1
  • Name
    methionyl aminopeptidase 1
  • Synonyms
    1700029C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922874
    NCBI Gene: 75624
  • Gene Overview
    MyGene.info: METAP1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:138458960-138489382 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 64.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922874
protein coding gene Chr3:138458956-138489515 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027932
protein coding gene Chr3:141509928-141540441 (-)
A/J MGP_AJ_G0027889
protein coding gene Chr3:136498711-136529110 (-)
AKR/J MGP_AKRJ_G0027855
protein coding gene Chr3:140122149-140152756 (-)
BALB/cJ MGP_BALBcJ_G0027901
protein coding gene Chr3:136310524-136340853 (-)
C3H/HeJ MGP_C3HHeJ_G0027631
protein coding gene Chr3:140465025-140496828 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028345
protein coding gene Chr3:146397149-146429267 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025683
protein coding gene Chr3:131914833-131946304 (-)
CAST/EiJ MGP_CASTEiJ_G0027087
protein coding gene Chr3:140227631-140271711 (-)
CBA/J MGP_CBAJ_G0027608
protein coding gene Chr3:151373581-151407146 (-)
DBA/2J MGP_DBA2J_G0027747
protein coding gene Chr3:135625305-135655675 (-)
FVB/NJ MGP_FVBNJ_G0027714
protein coding gene Chr3:133084922-133116250 (-)
LP/J MGP_LPJ_G0027857
protein coding gene Chr3:142904470-142941726 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027746
protein coding gene Chr3:159481031-159512875 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028403
protein coding gene Chr3:139676192-139708296 (-)
PWK/PhJ MGP_PWKPhJ_G0026811
protein coding gene Chr3:135381964-135423191 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026638
protein coding gene Chr3:137784345-137826642 (-)
WSB/EiJ MGP_WSBEiJ_G0027166
protein coding gene Chr3:140525986-140564407 (-)



Homology
more
  • Human Ortholog
    METAP1, methionyl aminopeptidase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    METAP1, methionyl aminopeptidase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MAP1A, MetAP1A
  • Links
    NCBI Gene ID: 23173
    neXtProt AC: NX_P53582
    UniProt: P53582

  • Chr Location
    4q23; chr4:98995637-99062809 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75624 NCBI Gene Model | MGI Sequence Detail 30423 C57BL/6J ±  kb
transcript NM_175224 RefSeq | MGI Sequence Detail 2549 C57BL/6  
polypeptide Q8BP48 UniProt | EBI | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    cDNA 88

    Microarray probesets 7
Other
Accession IDs
less
MGI:2139953
References
more
  • Summaries
    All 27
    Diseases 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/11/2018
MGI 6.13
The Jackson Laboratory