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Metap1 Gene Detail
Summary
  • Symbol
    Metap1
  • Name
    methionyl aminopeptidase 1
  • Synonyms
    1700029C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922874
    NCBI Gene: 75624
  • Gene Overview
    MyGene.info: METAP1
Location & Maps
more
  • Sequence Map
    Chr3:138458956-138489515 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30560 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 64.27 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    METAP1, methionyl aminopeptidase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    METAP1, methionyl aminopeptidase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MAP1A, MetAP1A
  • Links
    NCBI Gene ID: 23173
    neXtProt AC: NX_P53582

  • Chr Location
    4q23; chr4:98995637-99062809 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    11
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Metap1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052836 VEGA Gene Model | MGI Sequence Detail 30560 C57BL/6J ±  kb
transcript OTTMUST00000132230 VEGA | MGI Sequence Detail 2686 Not Applicable  
polypeptide OTTMUSP00000070523 VEGA | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    146 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000010336 methionine aminopeptidase 1
  • EC
  • InterPro Domains
    IPR031615 MYND-like zinc finger, mRNA-binding
    IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1
    IPR001714 Peptidase M24, methionine aminopeptidase
    IPR000994 Peptidase M24, structural domain
Molecular
Reagents
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  • All nucleic 86
    cDNA 86

    Microarray probesets 7
Other
Accession IDs
less
MGI:2139953
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory