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Spaca3 Gene Detail
Summary
  • Symbol
    Spaca3
  • Name
    sperm acrosome associated 3
  • Synonyms
    1700025M08Rik, ALLP17, SLLP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922872
    NCBI Gene: 75622
  • Gene Overview
    MyGene.info: SPACA3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:80858389-80867814 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 48.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922872
protein coding gene Chr11:80858365-80867814 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018817
protein coding gene Chr11:82042770-82052708 (+)
A/J MGP_AJ_G0018784
protein coding gene Chr11:78896404-78906706 (+)
AKR/J MGP_AKRJ_G0018754
protein coding gene Chr11:81242555-81251538 (+)
BALB/cJ MGP_BALBcJ_G0018757
protein coding gene Chr11:79291737-79301263 (+)
C3H/HeJ MGP_C3HHeJ_G0018571
protein coding gene Chr11:81321521-81331324 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019209
protein coding gene Chr11:84543543-84557007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016843
protein coding gene Chr11:75820242-75829272 (+)
CAST/EiJ MGP_CASTEiJ_G0018126
protein coding gene Chr11:81806930-81819248 (+)
CBA/J MGP_CBAJ_G0018542
protein coding gene Chr11:88259411-88276806 (+)
DBA/2J MGP_DBA2J_G0018650
protein coding gene Chr11:78449583-78460478 (+)
FVB/NJ MGP_FVBNJ_G0018639
protein coding gene Chr11:78012347-78021678 (+)
LP/J MGP_LPJ_G0018720
protein coding gene Chr11:82566661-82576914 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018666
protein coding gene Chr11:88515788-88528019 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019249
protein coding gene Chr11:81534201-81544667 (+)
PWK/PhJ MGP_PWKPhJ_G0017896
protein coding gene Chr11:79267373-79277992 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017687
protein coding gene Chr11:81127787-81139404 (+)
WSB/EiJ MGP_WSBEiJ_G0018178
protein coding gene Chr11:81365127-81380493 (+)



Homology
more
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALLP17, CT54, LYC3, LYZC, LYZL3, SLLP1
  • Links
    NCBI Gene ID: 124912
    neXtProt AC: NX_Q8IXA5
    UniProt: Q8IXA5

  • Chr Location
    17q11.2; chr17:32991864-32997877 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Spaca3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75622 NCBI Gene Model | MGI Sequence Detail 9426 C57BL/6J ±  kb
transcript NM_001359183 RefSeq | MGI Sequence Detail 953 C57BL/6  
polypeptide Q9D9X8 UniProt | EBI | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory