Chmp4b
Gene Detail

Symbol Name ID

Chmp4b charged multivesicular body protein 4B MGI:1922858

Synonyms

2010012F05Rik, chromatin modifying protein 4B, Snf7-2

Feature Type

protein coding gene

Genetic Map

Chromosome 2

76.79 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:154651705-154694785 bp, + strand From VEGA annotation of GRCm38   43081 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:57102  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ESCRT-3 complex, Chmp4/Chmp5/Chmp6 subunits
Gene Tree: Chmp4b

Human homologs

Human Homolog		CHMP4B, charged multivesicular body protein 4B
NCBI Gene ID		128866
neXtProt AC		NX_Q9H444
Human Synonyms		C20orf178, CHMP4A, CTPP3, dJ553F4.4, Shax1, SNF7, SNF7-2, Vps32-2, VPS32B
Human Chr (Location)		20q11.22; chr20:32399110-32442173 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CHMP4B

Alleles and phenotypes

All alleles(53) : Targeted(2) Gene trapped(51)
 

Mice homozygous for a gene trap insertion die between E7.5 and E8.5.

 

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	protein transport, transport
Component	cytoplasm, endosome, ...

External Resources: FuncBase

Expression

cDNA source data(112)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(112) cDNA(112)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000015914 (Evidence)
Ensembl Gene Model	ENSMUSG00000038467 (Evidence)
Entrez Gene	75608 (Evidence)
UniGene	262480
DFCI	TC1574209, TC1659160
DoTS	DT.101400108, DT.101400110, DT.533201
NIA Mouse Gene Index	U002691
Consensus CDS Project	CCDS16938.1
International Mouse Knockout Project Status	Chmp4b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015914	VEGA Gene Model | MGI Sequence Detail	43081	C57BL/6J
transcript	OTTMUST00000037805	VEGA | MGI Sequence Detail	1616	Not Applicable
polypeptide	OTTMUSP00000016972	VEGA | MGI Sequence Detail	224	Not Applicable

All sequences(35) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(168 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005024	Snf7
Protein Ontology	PR:000005437	charged multivesicular body protein 4b

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGI:2139458