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Chmp4b
Gene Detail
Symbol

Name
ID
Chmp4b
charged multivesicular body protein 4B
MGI:1922858
Synonyms
2010012F05Rik, chromatin modifying protein 4B, Snf7-2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
76.79 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:154651705-154694785 bp, + strand
From VEGA annotation of GRCm38

  43081 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57102  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ESCRT-3 complex, Chmp4/Chmp5/Chmp6 subunits
Gene Tree: Chmp4b

Human
homologs
Human Homolog CHMP4B, charged multivesicular body protein 4B
NCBI Gene ID 128866
neXtProt AC  NX_Q9H444
Human Synonyms  C20orf178, CHMP4A, CTPP3, CTRCT31, dJ553F4.4, Shax1, SNF7, SNF7-2, Vps32-2, VPS32B
Human Chr (Location)  20q11.22; chr20:33811304-33854367 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CHMP4B
Mutations,
alleles, and
phenotypes
All mutations/alleles(53) : Gene trapped(51) Targeted(2)
 
Mice homozygous for a gene trap insertion die between E7.5 and E8.5.
 
Interactions
Chmp4b interacts with 146 markers (Mir10a, Mir15a, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(112)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(112) cDNA(112)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000015914 (Evidence)
Ensembl Gene ModelENSMUSG00000038467 (Evidence)
Entrez Gene75608 (Evidence)
UniGene262480
DFCITC1659160, TC1574209
DoTSDT.533201, DT.101400110, DT.101400108
NIA Mouse Gene IndexU002691
Consensus CDS ProjectCCDS16938.1
International Mouse Knockout Project StatusChmp4b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015914 VEGA Gene Model | MGI Sequence Detail 43081 C57BL/6J ±  kb
transcript OTTMUST00000037805 VEGA | MGI Sequence Detail 1616 Not Applicable 
polypeptide OTTMUSP00000016972 VEGA | MGI Sequence Detail 224 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(325 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005024 Snf7
Protein Ontology PR:000005437 charged multivesicular body protein 4b
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2139458

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory