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Trir Gene Detail
Summary
  • Symbol
    Trir
  • Name
    telomerase RNA component interacting RNase
  • Synonyms
    1110002H14Rik, 2310036O22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922833
    NCBI Gene: 68544
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85026823-85030286 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.49 cM, cytoband C3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922833
protein coding gene Chr8:85026812-85030286 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033888
protein coding gene Chr8:85972725-85976165 (+)
A/J MGP_AJ_G0033871
protein coding gene Chr8:82574456-82577904 (+)
AKR/J MGP_AKRJ_G0033797
protein coding gene Chr8:85027998-85031438 (+)
BALB/cJ MGP_BALBcJ_G0033864
protein coding gene Chr8:82710993-82714431 (+)
C3H/HeJ MGP_C3HHeJ_G0033574
protein coding gene Chr8:85648227-85651675 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034384
protein coding gene Chr8:89260633-89264083 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031325
protein coding gene Chr8:76376815-76380237 (+)
CAST/EiJ MGP_CASTEiJ_G0032904
protein coding gene Chr8:85079974-85083394 (+)
CBA/J MGP_CBAJ_G0033550
protein coding gene Chr8:92283486-92286934 (+)
DBA/2J MGP_DBA2J_G0033703
protein coding gene Chr8:82213916-82217362 (+)
FVB/NJ MGP_FVBNJ_G0033651
protein coding gene Chr8:81172327-81175775 (+)
LP/J MGP_LPJ_G0033795
protein coding gene Chr8:86074172-86077612 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033693
protein coding gene Chr8:94853290-94856736 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034401
protein coding gene Chr8:85016263-85019715 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0032444
protein coding gene Chr8:83824927-83828360 (+)
WSB/EiJ MGP_WSBEiJ_G0033017
protein coding gene Chr8:85443701-85447149 (+)



Homology
more
  • Human Ortholog
    TRIR, telomerase RNA component interacting RNase
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TRIR, telomerase RNA component interacting RNase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C19orf43, fSAP18, TERCIR
  • Links
    NCBI Gene ID: 79002
    neXtProt AC: NX_Q9BQ61
    UniProt: Q9BQ61

  • Chr Location
    19p13.13; chr19:12730640-12734715 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Trir
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041203 Ensembl Gene Model | MGI Sequence Detail 3464 C57BL/6J ±  kb
transcript ENSMUST00000047281 Ensembl | MGI Sequence Detail 902 Not Applicable  
polypeptide ENSMUSP00000044129 Ensembl | MGI Sequence Detail 173 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 100
    cDNA 100

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915794, MGI:2142644
References
more
  • Summaries
    All 56
    Gene Ontology 4
    Phenotypes 30
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory