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Eppin
Gene Detail
Symbol

Name
ID
Eppin
epididymal peptidase inhibitor
MGI:1922776
Synonyms
1700024E17Rik, Spinlw1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
85.21 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:164588343-164593594 bp, - strand
From VEGA annotation of GRCm38

  5252 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41775  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle

HCOP human homology predictions: EPPIN, EPPIN-WFDC6
Gene Tree: Eppin

Human
homologs
EPPIN, epididymal peptidase inhibitor
Orthology source: HGNC

IDs:
NCBI Gene ID: 57119
neXtProt AC: NX_O95925

Human Synonyms: CT71, CT72, dJ461P17.2, SPINLW1, WAP7, WFDC7

Human Chr (Location): 20q13.12; chr20:45540626-45547426 (-)  GRCh38.p2

  1 More Homolog(s):
Mutations,
alleles, and
phenotypes
Incidental mutations (data from APF )
Interactions
Eppin interacts with 51 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of peptidase activity
Component acrosomal vesicle, cytoplasm, ...
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000001094 (Evidence)
Ensembl Gene Model ENSMUSG00000017733 (Evidence)
Entrez Gene 75526 (Evidence)
UniGene 159533
DFCI TC1590674
DoTS DT.91325993
Consensus CDS Project CCDS17043.1
International Mouse Phenotyping Consortium Status Eppin
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001094 VEGA Gene Model | MGI Sequence Detail 5252 C57BL/6J ±  kb
transcript OTTMUST00000002150 VEGA | MGI Sequence Detail 778 Not Applicable 
polypeptide OTTMUSP00000001048 VEGA | MGI Sequence Detail 134 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
Protein Ontology PR:000015541 eppin
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:171630 Bagheri-Fam S, et al., Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet. 2011 Jun 1;20(11):2213-24
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory