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Eppin
Gene Detail
 Symbol
Name
ID
Eppin
epididymal peptidase inhibitor
MGI:1922776
Synonyms 1700024E17Rik, Spinlw1
Feature Type protein coding gene
Genetic Map
Chromosome 2
85.21 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:164588343-164593594 bp, - strand
From VEGA annotation of GRCm38

  5252 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41775  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle

Gene Tree: Eppin

Human
homologs
Human Homolog EPPIN-WFDC6, EPPIN-WFDC6 readthrough
NCBI Gene ID 100526773
neXtProt AC  NX_O95925
Human Synonyms  SPINLW1-WFDC6
Human Chr (Location)  20q; chr20:45536280-45547426 (-)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from APF )
Interactions
Eppin interacts with 51 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of peptidase activity
Component acrosomal vesicle, cytoplasm, ...
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000001094 (Evidence)
Ensembl Gene ModelENSMUSG00000017733 (Evidence)
Entrez Gene75526 (Evidence)
UniGene159533
DFCITC1590674
DoTSDT.91325993
Consensus CDS ProjectCCDS17043.1
International Mouse Knockout Project StatusEppin
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001094 VEGA Gene Model | MGI Sequence Detail 5252 C57BL/6J ±  kb
transcript OTTMUST00000002150 VEGA | MGI Sequence Detail 778 Not Applicable 
polypeptide OTTMUSP00000001048 VEGA | MGI Sequence Detail 134 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
Protein Ontology PR:000015541 eppin
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:171630 Bagheri-Fam S, et al., Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet. 2011 Jun 1;20(11):2213-24
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory