About   Help   FAQ
Gpx6
Gene Detail
Symbol

Name
ID
Gpx6
glutathione peroxidase 6
MGI:1922762
Synonyms
1700020G18Rik, olfactory
Feature Type
protein coding gene
Genetic Map
Chromosome 13
7.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:21312217-21319624 bp, + strand
From VEGA annotation of GRCm38

  7408 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:130008  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: glutathione peroxidase
Gene Tree: Gpx6

Human
homologs
Human Homolog GPX6, glutathione peroxidase 6 (olfactory)
NCBI Gene ID 257202
neXtProt AC  NX_P59796
Human Synonyms  dJ1186N24, dJ1186N24.1, GPX5p, GPx-6, GPXP3, GSHPx-6
Human Chr (Location)  6p22.1; chr6:28503296-28515793 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gpx6 interacts with 86 markers (Mir22, Mir25, Mir29b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process oxidation-reduction process, response to oxidative stress
Component extracellular region
Function glutathione peroxidase activity, oxidoreductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (136)    Tissues (136)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 136
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000000419 (Evidence)
Ensembl Gene ModelENSMUSG00000004341 (Evidence)
Entrez Gene75512 (Evidence)
UniGene46195
DFCITC1585056, TC1662354
DoTSDT.40144359
NIA Mouse Gene IndexU014594
EC1.11.1.9
Consensus CDS ProjectCCDS26271.1
International Mouse Knockout Project StatusGpx6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000419 VEGA Gene Model | MGI Sequence Detail 7408 C57BL/6J ±  kb
transcript OTTMUST00000000997 VEGA | MGI Sequence Detail 1244 Not Applicable 
polypeptide OTTMUSP00000000445 VEGA | MGI Sequence Detail 221 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000889 Glutathione peroxidase
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008215 glutathione peroxidase 6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory