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Gpx6 Gene Detail
Summary
  • Symbol
    Gpx6
  • Name
    glutathione peroxidase 6
  • Synonyms
    1700020G18Rik, olfactory
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922762
    NCBI Gene: 75512
  • Gene Overview
    MyGene.info: GPX6
Location & Maps
more
  • Sequence Map
    Chr13:21312217-21319624 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7408 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 7.74 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GPX6, glutathione peroxidase 6
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GPX6, glutathione peroxidase 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    dJ1186N24, dJ1186N24.1, GPX5p, GPx-6, GPXP3, GSHPx-6
  • Links
    NCBI Gene ID: 257202
    neXtProt AC: NX_P59796

  • Chr Location
    6p22.1; chr6:28503296-28515793 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Gpx6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000419 VEGA Gene Model | MGI Sequence Detail 7408 C57BL/6J ±  kb
transcript OTTMUST00000000997 VEGA | MGI Sequence Detail 1244 Not Applicable  
polypeptide OTTMUSP00000000445 VEGA | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    102 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218239 Shema R, et al., Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington's disease. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):268-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory