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Pou5f2
Gene Detail
 Symbol
Name
ID
Pou5f2
POU domain class 5, transcription factor 2
MGI:1922757
Synonyms 1700013G10Rik, Sprm1
Feature Type protein coding gene
Genetic Map
Chromosome 13
41.38 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:78024902-78026294 bp, + strand
From VEGA annotation of GRCm38

  1393 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:83454  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee

Protein SuperFamily: transcription factor Oct-3
Gene Tree: Pou5f2

Human
homologs
Human Homolog POU5F2, POU domain class 5, transcription factor 2
NCBI Gene ID 134187
neXtProt AC  NX_Q8N7G0
Human Synonyms  SPRM-1
Human Chr (Location)  5q15; chr5:93740309-93741603 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null male mice exhibit reduced male fertility in spite of normal morphology and sperm count.
 
Interactions
Pou5f2 interacts with 69 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component nucleus
Function DNA binding, sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (86)    Tissues (46)    Images (3)
Theiler Stages: 21, 23, 28
Assay TypeResults
RNA in situ 86
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000039919 (Evidence)
Ensembl Gene ModelENSMUSG00000093668 (Evidence)
Entrez Gene75507 (Evidence)
DFCITC1588836
DoTSDT.110974535, DT.60105148
NIA Mouse Gene IndexU150391
Consensus CDS ProjectCCDS56895.1
International Mouse Knockout Project StatusPou5f2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000039919 VEGA Gene Model | MGI Sequence Detail 1393 C57BL/6J ±  kb
transcript OTTMUST00000103739 VEGA | MGI Sequence Detail 1393 Not Applicable 
polypeptide OTTMUSP00000057985 VEGA | MGI Sequence Detail 329 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR010982 Lambda repressor-like, DNA-binding domain
InterPro IPR013847 POU domain
InterPro IPR000327 POU-specific
Protein Ontology PR:000013045 POU domain, class 5, transcription factor 2
References (Earliest) J:15132 Xia YR, et al., Chromosomal organization of mammalian POU domain factors. Genomics. 1993 Oct;18(1):126-30
(Latest) J:204898 Akiyama K, et al., A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. J Biol Chem. 2013 Nov 1;288(44):31830-41
All references(33)
Other
accession IDs
MGD-MRK-19580, MGI:102677

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory