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Cfap126 Gene Detail
Summary
  • Symbol
    Cfap126
  • Name
    cilia and flagella associated protein 126
  • Synonyms
    1700009P17Rik, Flattop, Fltp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922722
    NCBI Gene: 75472
Location & Maps
more
  • Sequence Map
    Chr1:171113918-171126967 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13050 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CFAP126, cilia and flagella associated protein 126
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CFAP126, cilia and flagella associated protein 126
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1orf192, Flattop, Fltp
  • Links
    NCBI Gene ID: 257177
    neXtProt AC: NX_Q5VTH2

  • Chr Location
    1q23.3; chr1:161364731-161367883 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    2
  • Gene trapped
    14
  • Targeted
    4
  • Genomic Mutations
    2 involving Cfap126
  • Incidental Mutations
Mice homozygous for a knock-in allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021658 VEGA Gene Model | MGI Sequence Detail 13050 C57BL/6J ±  kb
transcript OTTMUST00000051411 VEGA | MGI Sequence Detail 766 Not Applicable  
polypeptide OTTMUSP00000024184 VEGA | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    164 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2138531
References
more
  • Summaries
    All 26
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:215971 Gegg M, et al., Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife. 2014;3

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory