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Cfap126
Gene Detail
Symbol

Name
ID
Cfap126
cilia and flagella associated protein 126
MGI:1922722
Synonyms
1700009P17Rik, Flattop, Fltp
Feature Type
protein coding gene
Genetic Map
Chromosome 1
78.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:171113918-171126967 bp, + strand
From VEGA annotation of GRCm38

  13050 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23682  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: CFAP126
Gene Tree: Cfap126

Human
homologs
CFAP126, cilia and flagella associated protein 126
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 257177
neXtProt AC: NX_Q5VTH2

Human Synonyms: C1orf192, Flattop, Fltp

Human Chr (Location): 1q23.3; chr1:161364731-161367883 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(14) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-in allele are viable and fertile.
 
Interactions
Cfap126 interacts with 35 markers (Mir33, Mir204, Mir211, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell projection organization, cilium organization
Component apical plasma membrane, cell projection, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (73)    Tissues (26)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 55
In situ reporter (knock in) 2
Western blot 1
RT-PCR 15
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000021658 (Evidence)
Ensembl Gene Model ENSMUSG00000026649 (Evidence)
Entrez Gene 75472 (Evidence)
UniGene 32760
DFCI TC1585975
DoTS DT.50315308
NIA Mouse Gene Index U001077
Consensus CDS Project CCDS35771.1
International Mouse Phenotyping Consortium Status Cfap126
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021658 VEGA Gene Model | MGI Sequence Detail 13050 C57BL/6J ±  kb
transcript OTTMUST00000051411 VEGA | MGI Sequence Detail 766 Not Applicable 
polypeptide OTTMUSP00000024184 VEGA | MGI Sequence Detail 233 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(18) UniProt(7)
Polymorphisms
SNPs within 2kb(167 from dbSNP Build 137)
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:215971 Gegg M, et al., Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife. 2014;3
All references(29)
Other
accession IDs
MGI:2138531

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory