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Syce3
Gene Detail
Symbol

Name
ID
Syce3
synaptonemal complex central element protein 3
MGI:1922709
Synonyms
1700007E06Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:89390174-89410503 bp, - strand
From VEGA annotation of GRCm38

  20330 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:85810  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SYCE3
Gene Tree: Syce3

Human
homologs
SYCE3, synaptonemal complex central element protein 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 644186
neXtProt AC: NX_A1L190

Human Synonyms: C22orf41, THEG2

Human Chr (Location): 22q13.33; chr22:50551112-50562899 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Radiation induced(1) Targeted(1)
Genomic Mutations involving Syce3 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display male and female infertility, impaired double strand break repair and absence of synapsis during meiosis, absence of mature gametes, and small testes and ovaries.
 
Phenotype Images(2)
Interactions
Syce3 interacts with 25 markers (Mir7-2, Mir7b, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell cycle, cell division, ...
Component central element, chromosome, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (13)    Tissues (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 13
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000049834 (Evidence)
Ensembl Gene Model ENSMUSG00000078938 (Evidence)
Entrez Gene 75459 (Evidence)
UniGene 45462
DFCI TC1657615, TC1667983
DoTS DT.94257739, DT.50315066, DT.101339823
NIA Mouse Gene Index U036533
PDB 4R3Q
Consensus CDS Project CCDS49703.1
International Mouse Phenotyping Consortium Status Syce3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049834 VEGA Gene Model | MGI Sequence Detail 20330 C57BL/6J ±  kb
transcript OTTMUST00000126916 VEGA | MGI Sequence Detail 448 Not Applicable 
polypeptide OTTMUSP00000068598 VEGA | MGI Sequence Detail 88 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000032487 synaptonemal complex central element protein 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205574 Shibuya H, et al., The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis. Nat Cell Biol. 2014 Feb;16(2):145-56
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory