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Syce3
Gene Detail
 Symbol
Name
ID
Syce3
synaptonemal complex central element protein 3
MGI:1922709
Synonyms 1700007E06Rik
Feature Type protein coding gene
Genetic Map
Chromosome 15
44.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:89390174-89410503 bp, - strand
From NCBI annotation of GRCm38

  20330 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:85810  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Syce3

Human
homologs
Human Homolog SYCE3, synaptonemal complex central element protein 3
NCBI Gene ID 644186
neXtProt AC  NX_A1L190
Human Synonyms  C22orf41, THEG2
Human Chr (Location)  22q13.33; chr22:50551112-50562899 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Radiation induced(1) Targeted(1)
Genomic Mutations involving Syce3 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display male and female infertility, impaired double strand break repair and absence of synapsis during meiosis, absence of mature gametes, and small testes and ovaries.
 
Interactions
Syce3 interacts with 25 markers (Mir7-2, Mir7b, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell cycle, cell division, ...
Component central element, chromosome, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000078938 (Evidence)
Entrez Gene75459 (Evidence)
UniGene45462
DFCITC1657615, TC1667983
DoTSDT.101339823, DT.50315066, DT.94257739
NIA Mouse Gene IndexU036533
Consensus CDS ProjectCCDS49703.1
International Mouse Knockout Project StatusSyce3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 75459 NCBI Gene Model | MGI Sequence Detail 20330 C57BL/6J ±  kb
transcript NM_001162880 RefSeq | MGI Sequence Detail 510 Not Specified 
polypeptide B5KM66 UniProt | EBI | MGI Sequence Detail 88 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000032487 synaptonemal complex central element protein 3
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205574 Shibuya H, et al., The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis. Nat Cell Biol. 2014 Feb;16(2):145-56
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory