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Cfap97d1 Gene Detail
Summary
  • Symbol
    Cfap97d1
  • Name
    CFAP97 domain containing 1
  • Synonyms
    1700006E09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922687
    NCBI Gene: 75437
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101877882-101883090 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 65.48 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922687
protein coding gene Chr11:101875105-101883090 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019216
protein coding gene Chr11:104925662-104933620 (+)
A/J MGP_AJ_G0019184
protein coding gene Chr11:100495252-100503245 (+)
AKR/J MGP_AKRJ_G0019153
protein coding gene Chr11:103609472-103617429 (+)
BALB/cJ MGP_BALBcJ_G0019158
protein coding gene Chr11:100979591-100987549 (+)
C3H/HeJ MGP_C3HHeJ_G0018967
protein coding gene Chr11:103813057-103821015 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019607
protein coding gene Chr11:108197971-108205956 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017233
protein coding gene Chr11:97919430-97927502 (+)
CAST/EiJ MGP_CASTEiJ_G0018521
protein coding gene Chr11:104777661-104785630 (+)
CBA/J MGP_CBAJ_G0018936
protein coding gene Chr11:112662633-112670618 (+)
DBA/2J MGP_DBA2J_G0019048
protein coding gene Chr11:100020658-100028791 (+)
FVB/NJ MGP_FVBNJ_G0019038
protein coding gene Chr11:99547029-99555014 (+)
LP/J MGP_LPJ_G0019117
protein coding gene Chr11:105442457-105450415 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019069
protein coding gene Chr11:112191601-112199559 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019645
protein coding gene Chr11:103969460-103977428 (+)
PWK/PhJ MGP_PWKPhJ_G0018284
protein coding gene Chr11:101080602-101088813 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018076
protein coding gene Chr11:103717036-103724998 (+)
WSB/EiJ MGP_WSBEiJ_G0018570
protein coding gene Chr11:103954655-103962654 (+)



Homology
more
  • Human Ortholog
    CFAP97D1, CFAP97 domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP97D1, CFAP97 domain containing 1
  • Synonyms
    C17orf105
  • Links
    NCBI Gene ID: 284067
    neXtProt AC: NX_B2RV13
    UniProt: B2RV13

  • Chr Location
    17q21.31; chr17:43778391-43784842 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced male fertility associated with impaired sperm penetration of zona pellucida, asthenozoospermia, and abnormal axoneme structure.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75437 NCBI Gene Model | MGI Sequence Detail 5209 C57BL/6J ±  kb
    transcript NM_029287 RefSeq | MGI Sequence Detail 698 C57BL/6  
    polypeptide Q9DAN9 UniProt | EBI | MGI Sequence Detail 164 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR038792 CFAP97 domain-containing protein 1/2
      IPR029488 Hemingway/CFA97
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Gene Ontology 1
      Phenotypes 10
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:294173 Oura S, et al., Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility. PLoS Genet. 2020 Aug;16(8):e1008954

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/07/2021
    MGI 6.17
    The Jackson Laboratory