Cimip2c Gene Detail

Summary

• Symbol
  Cimip2c
• Name
  ciliary microtubule inner protein 2C
• Synonyms
  1700001C02Rik, 1700047H18Rik, Fam166c

• Feature Type
  protein coding gene
• IDs
  MGI:1922684
  NCBI Gene: 75434
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr5:30623395-30641433 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 16.57 cM, cytoband B1
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  129 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922684	protein coding gene	Chr5:30623391-30641433 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029390	protein coding gene	Chr5:28406287-28424169 (+)
A/J	MGP_AJ_G0029356	protein coding gene	Chr5:27477267-27495461 (+)
AKR/J	MGP_AKRJ_G0029307	protein coding gene	Chr5:28618029-28637706 (+)
BALB/cJ	MGP_BALBcJ_G0029367	protein coding gene	Chr5:28004143-28022167 (+)
C3H/HeJ	MGP_C3HHeJ_G0029088	protein coding gene	Chr5:28614136-28633461 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029820	protein coding gene	Chr5:30140425-30159936 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027058	protein coding gene	Chr5:24970337-24987804 (+)
CAST/EiJ	MGP_CASTEiJ_G0028499	protein coding gene	Chr5:27710199-27728206 (+)
CBA/J	MGP_CBAJ_G0029056	protein coding gene	Chr5:30736964-30757399 (+)
DBA/2J	MGP_DBA2J_G0029205	protein coding gene	Chr5:27665792-27684208 (+)
FVB/NJ	MGP_FVBNJ_G0029163	protein coding gene	Chr5:27077040-27095344 (+)
LP/J	MGP_LPJ_G0029290	protein coding gene	Chr5:28863671-28883131 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029192	protein coding gene	Chr5:31638205-31657539 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029854	protein coding gene	Chr5:28121882-28141216 (+)
PWK/PhJ	MGP_PWKPhJ_G0028223	protein coding gene	Chr5:26780106-26798182 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028054	protein coding gene	Chr5:27463351-27483467 (+)
WSB/EiJ	MGP_WSBEiJ_G0028579	protein coding gene	Chr5:28198906-28216957 (+)

Homology

• Human Ortholog
  CIMIP2C, ciliary microtubule inner protein 2C

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CIMIP2C, ciliary microtubule inner protein 2C
  
• Synonyms
  C2orf70, FAM166C
• Links
  HGNC:27938

  NCBI Gene ID: 339778

  neXtProt AC: NX_A6NJV1

  UniProt: A6NJV1

  
  
• Chr Location
  2p23.3; chr2:26562585-26579532 (+)  GRCh38

---

• MGI Vertebrate Homology
  Cimip2c stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CIMIP2C
• Gene Tree
  Cimip2c
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  28 phenotype references
  

• All Mutations and Alleles
  10
• Chemically induced (other)
  2
• Endonuclease-mediated
  1
• Gene trapped
  2
• Radiation induced
  3
• Spontaneous
  1
• Targeted
  1
• Genomic Mutations
  6 involving Cimip2c
• Find Mice (IMSR)
  13 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  3

Expression

• Assay Results
  747
• Tissues
  32
• cDNA Data
  11
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase cimip2c

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  8
• UniProt
  3
• CCDS
  CCDS19158.1

• Ensembl
  ENSMUSG00000029182 (Evidence)
• NCBI Gene
  75434

Representative Sequences			Length	Strain/Species
genomic	75434	NCBI Gene Model | MGI Sequence Detail	18039	C57BL/6J
transcript	NM_001417888	RefSeq | MGI Sequence Detail	863	C57BL/6
polypeptide	Q9DAS2	UniProt | EBI | MGI Sequence Detail	200	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000059704 ciliary microtubule inner protein 2C
  (term hierarchy)
• PDB
  8I7O, 8I7R, 8IYJ
• InterPro Domains
  IPR018902 Ciliary microtubule inner protein 2A-C-like

Molecular
Reagents

• All nucleic 12

  cDNA 11

  Primer pair 1

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1920619

References

• Summaries
  All 55

  Developmental Gene Expression 4

  Diseases 1

  Gene Ontology 3

  Phenotypes 28
• Earliest
  J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
• Latest
  J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19

TSS for Cimip2c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr45583	Chr5:30623388-30623436 (+)	17 bp