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Secisbp2
Gene Detail
Symbol

Name
ID
Secisbp2
SECIS binding protein 2
MGI:1922670
Synonyms
2210413N07Rik, 2810012K13Rik, SBP2
Feature Type
protein coding gene
Genetic Map
Chromosome 13
26.12 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:51651697-51684044 bp, + strand
From VEGA annotation of GRCm38

  32348 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11415  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SECISBP2
Gene Tree: Secisbp2

Human
homologs
SECISBP2, SECIS binding protein 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 79048
neXtProt AC: NX_Q96T21

Human Synonyms: SBP2

Human Chr (Location): 9q22.2; chr9:89318473-89367117 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SECISBP2

Mutations,
alleles, and
phenotypes
All mutations/alleles(18) : Gene trapped(15) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit complete preweaning lethality while heterozygotes exhibit reduced serum selenium levels.
 
Interactions
Secisbp2 interacts with 120 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (8)    Tissues (4)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 8
cDNA source data(54)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase secisbp2 ; ZFIN secisbp2    NEW 
Molecular
reagents
All nucleic(56) cDNA(56)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000020967 (Evidence)
Ensembl Gene Model ENSMUSG00000035139 (Evidence)
Entrez Gene 75420 (Evidence)
UniGene 275981
DFCI TC1582647, TC1598391, TC1642067
DoTS DT.101129080, DT.522817, DT.94256723
NIA Mouse Gene Index U014844
Consensus CDS Project CCDS36665.1
International Mouse Phenotyping Consortium Status Secisbp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020967 VEGA Gene Model | MGI Sequence Detail 32348 C57BL/6J ±  kb
transcript OTTMUST00000049571 VEGA | MGI Sequence Detail 3328 Not Applicable 
polypeptide OTTMUSP00000022992 VEGA | MGI Sequence Detail 858 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(15) UniProt(3)
Polymorphisms
SNPs within 2kb(190 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR029064 50S ribosomal protein L30e-like
InterPro IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45
Protein Ontology PR:000014601 selenocysteine insertion sequence-binding protein 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:213480 Seeher S, et al., Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice. Biochem J. 2014 Aug 15;462(1):67-75
All references(42)
Other
accession IDs
MGI:1919610

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory