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Arhgap12 Gene Detail
Summary
  • Symbol
    Arhgap12
  • Name
    Rho GTPase activating protein 12
  • Synonyms
    2810011M08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922665
    NCBI Gene: 75415
Location & Maps
more
  • Sequence Map
    Chr18:6024427-6136098 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      111672 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 4.46 cM, cytoband A1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARHGAP12, Rho GTPase activating protein 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARHGAP12, Rho GTPase activating protein 12
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 94134
    neXtProt AC: NX_Q8IWW6

  • Chr Location
    10p11.22; chr10:31805398-31928876 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
A null gene trap mutation resulted in no notable phenotype in homozygous mutant mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036618 VEGA Gene Model | MGI Sequence Detail 111672 C57BL/6J ±  kb
transcript OTTMUST00000114186 VEGA | MGI Sequence Detail 4162 Not Applicable  
polypeptide OTTMUSP00000063738 VEGA | MGI Sequence Detail 843 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    527 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:214438 Rudnicki A, et al., Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways. BMC Genomics. 2014;15:484

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory