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Ndufs7
Gene Detail
 Symbol
Name
ID
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
MGI:1922656
Synonyms 1010001M04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:80249121-80256794 bp, + strand
From VEGA annotation of GRCm38

  7674 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11535  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase (complex I), PSST/NdhK/NuoB subunit
Gene Tree: Ndufs7

Human
homologs
Human Homolog NDUFS7, NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NCBI Gene ID 374291
neXtProt AC  NX_O75251
Human Synonyms  CI-20, CI-20KD, MY017, PSST
Human Chr (Location)  19p13.3; chr19:1383661-1395589 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NDUFS7
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(12) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ndufs7 interacts with 6 markers (Mir30b, Mir299b, Mir325, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process mitochondrial respiratory chain complex I assembly, oxidation-reduction process, ...
Component mitochondrial inner membrane, mitochondrial respiratory chain complex I, ...
Function 4 iron, 4 sulfur cluster binding, iron-sulfur cluster binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (4)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000000012 (Evidence)
Ensembl Gene ModelENSMUSG00000020153 (Evidence)
Entrez Gene75406 (Evidence)
DFCITC1576039
DoTSDT.489921
NIA Mouse Gene IndexU011745
EC1.6.5.3, 1.6.99.3
Consensus CDS ProjectCCDS24015.1
International Mouse Knockout Project StatusNdufs7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000012 VEGA Gene Model | MGI Sequence Detail 7674 C57BL/6J ±  kb
transcript OTTMUST00000045757 VEGA | MGI Sequence Detail 983 Not Applicable 
polypeptide OTTMUSP00000020604 VEGA | MGI Sequence Detail 224 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit
InterPro IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit
Protein Ontology PR:000011102 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
References (Earliest) J:36760 Hyslop SJ, et al., Assignment of the PSST subunit gene of human mitochondrial complex I to chromosome 19p13. Genomics. 1996 Nov 1;37(3):375-80
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory