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Ndufs7 Gene Detail
Summary
  • Symbol
    Ndufs7
  • Name
    NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • Synonyms
    1010001M04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922656
    NCBI Gene: 75406
  • Gene Overview
    MyGene.info: NDUFS7
Location & Maps
more
  • Sequence Map
    Chr10:80249121-80256794 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7674 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    NDUFS7, NADH:ubiquinone oxidoreductase core subunit S7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFS7, NADH:ubiquinone oxidoreductase core subunit S7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CI-20, CI-20KD, MY017, PSST
  • Links
    NCBI Gene ID: 374291
    neXtProt AC: NX_O75251

  • Chr Location
    19p13.3; chr19:1383884-1395589 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NDUFS7 associations

Human Disease Mouse Models
       Leigh Syndrome; LS   OMIM: 256000
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Targeted
    4
  • Genomic Mutations
    1 involving Ndufs7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000012 VEGA Gene Model | MGI Sequence Detail 7674 C57BL/6J ±  kb
transcript OTTMUST00000045757 VEGA | MGI Sequence Detail 983 Not Applicable  
polypeptide OTTMUSP00000020604 VEGA | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    13 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory