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Spp2 Gene Detail
Summary
  • Symbol
    Spp2
  • Name
    secreted phosphoprotein 2
  • Synonyms
    0610038O04Rik, spp24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922646
    NCBI Gene: 75396
Location & Maps
more
  • Sequence Map
    Chr1:88406961-88426438 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19478 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 44.63 cM, cytoband C5
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SPP2, secreted phosphoprotein 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SPP2, secreted phosphoprotein 2
    Orthology source: HomoloGene
  • Synonyms
    SPP24, SPP-24
  • Links
    NCBI Gene ID: 6694
    neXtProt AC: NX_Q13103

  • Chr Location
    2q37.1; chr2:234050690-234077134 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Spp2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020812 VEGA Gene Model | MGI Sequence Detail 19478 C57BL/6J ±  kb
transcript OTTMUST00000049220 VEGA | MGI Sequence Detail 928 Not Applicable  
polypeptide OTTMUSP00000022766 VEGA | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    107 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015562 secreted phosphoprotein 24
  • InterPro Domains
    IPR010892 Secreted phosphoprotein 24
Molecular
Reagents
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  • All nucleic 52
    cDNA 51
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194051 Heliot C, et al., HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory