About   Help   FAQ
Boll Gene Detail
Summary
  • Symbol
    Boll
  • Name
    boule homolog, RNA binding protein
  • Synonyms
    4930554P13Rik, 4930597B14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922638
    NCBI Gene: 75388
  • Gene Overview
    MyGene.info: BOLL
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr1:55248658-55363469 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      114812 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 28.08 cM, cytoband C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    BOLL, boule homolog, RNA binding protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    BOLL, boule homolog, RNA binding protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BOULE
  • Links
    NCBI Gene ID: 66037
    neXtProt AC: NX_Q8N9W6
    UniProt: Q8N9W6

  • Chr Location
    2q33.1; chr2:197726879-197786574 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Male mice homozygous for a knock-out allele exhibit infertility due to arrested spermatogenesis at step 6 in spermiogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000030118 VEGA Gene Model | MGI Sequence Detail 114812 C57BL/6J ±  kb
    transcript OTTMUST00000074610 VEGA | MGI Sequence Detail 882 Not Applicable  
    polypeptide OTTMUSP00000038930 VEGA | MGI Sequence Detail 293 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      552 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR037366 BOULE/DAZ family
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 5
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1922548
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:263202 Ungewitter EK, et al., Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. Sci Rep. 2018 Jun 25;8(1):9662

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    09/11/2018
    MGI 6.12
    The Jackson Laboratory