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Parpbp Gene Detail
Summary
  • Symbol
    Parpbp
  • Name
    PARP1 binding protein
  • Synonyms
    4930547N16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922567
    NCBI Gene: 75317
Location & Maps
more
  • Sequence Map
    Chr10:88091432-88146941 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      55510 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 43.70 cM, cytoband C2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PARPBP, PARP1 binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PARPBP, PARP1 binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AROM, C12orf48, PARI
  • Links
    NCBI Gene ID: 55010
    neXtProt AC: NX_Q9NWS1

  • Chr Location
    12q23.2; chr12:102120171-102197520 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49519
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PARPBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    6
  • Genomic Mutations
    1 involving Parpbp
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035174 VEGA Gene Model | MGI Sequence Detail 55510 C57BL/6J ±  kb
transcript OTTMUST00000089594 VEGA | MGI Sequence Detail 3594 Not Applicable  
polypeptide OTTMUSP00000048986 VEGA | MGI Sequence Detail 573 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    482 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143631
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:231879 Sokolowski K, et al., Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei. Neural Dev. 2016;11(1):12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory