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Fgfr1op Gene Detail
Summary
  • Symbol
    Fgfr1op
  • Name
    Fgfr1 oncogene partner
  • Synonyms
    4930553O10Rik, Fop
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922546
    NCBI Gene: 75296
  • Gene Overview
    MyGene.info: FGFR1OP
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:8165491-8196477 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 4.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922546
protein coding gene Chr17:8165491-8196804 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023129
protein coding gene Chr17:5634964-5666097 (+)
A/J MGP_AJ_G0023097
protein coding gene Chr17:5667556-5699606 (+)
AKR/J MGP_AKRJ_G0023062
protein coding gene Chr17:5326314-5357428 (+)
BALB/cJ MGP_BALBcJ_G0023097
protein coding gene Chr17:5475459-5503314 (+)
C3H/HeJ MGP_C3HHeJ_G0022860
protein coding gene Chr17:5610921-5639180 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023541
protein coding gene Chr17:5900865-5933990 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021067
protein coding gene Chr17:8657719-8689335 (-)
CAST/EiJ MGP_CASTEiJ_G0022371
protein coding gene Chr17:5346772-5619579 (+)
CBA/J MGP_CBAJ_G0022832
protein coding gene Chr17:6106106-6139624 (+)
DBA/2J MGP_DBA2J_G0022965
protein coding gene Chr17:5342692-5370691 (+)
FVB/NJ MGP_FVBNJ_G0022934
protein coding gene Chr17:5259896-5291018 (+)
LP/J MGP_LPJ_G0023036
protein coding gene Chr17:5449297-5476697 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022955
protein coding gene Chr17:5853071-5885552 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023566
protein coding gene Chr17:5614090-5645093 (+)
PWK/PhJ MGP_PWKPhJ_G0022123
protein coding gene Chr17:4958368-4990338 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021952
protein coding gene Chr17:4876453-4907878 (+)
WSB/EiJ MGP_WSBEiJ_G0022431
protein coding gene Chr17:5691016-5942644 (+)



Homology
more
  • Human Ortholog
    FGFR1OP, FGFR1 oncogene partner
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FGFR1OP, FGFR1 oncogene partner
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FOP
  • Links
    NCBI Gene ID: 11116
    neXtProt AC: NX_O95684
    UniProt: O95684

  • Chr Location
    6q27; chr6:166999317-167042418 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75296 NCBI Gene Model | MGI Sequence Detail 30987 C57BL/6J ±  kb
transcript NM_001197046 RefSeq | MGI Sequence Detail 3171 C57BL/6  
polypeptide Q66JX5 UniProt | EBI | MGI Sequence Detail 399 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 68

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265810 Cabaud O, et al., Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy. Hum Mol Genet. 2018 Oct 1;27(19):3377-3391

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory