About   Help   FAQ
Sv2c Gene Detail
Summary
  • Symbol
    Sv2c
  • Name
    synaptic vesicle glycoprotein 2c
  • Synonyms
    4930527L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922459
    NCBI Gene: 75209
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:95959443-96132577 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 50.47 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922459
 protein coding gene Chr13:95954594-96132577 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020846
 protein coding gene Chr13:97456301-97640404 (-)
A/J MGP_AJ_G0020800
 protein coding gene Chr13:93797292-93974190 (-)
AKR/J MGP_AKRJ_G0020774
 protein coding gene Chr13:96660802-96850924 (-)
BALB/cJ MGP_BALBcJ_G0020797
 protein coding gene Chr13:94476487-94656463 (-)
C3H/HeJ MGP_C3HHeJ_G0020590
 protein coding gene Chr13:96354073-96540907 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021233
 protein coding gene Chr13:100407054-100610992 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018802
 protein coding gene Chr13:89609917-89790573 (-)
CAST/EiJ MGP_CASTEiJ_G0020109
 protein coding gene Chr13:95661903-95849576 (-)
CBA/J MGP_CBAJ_G0020549
 protein coding gene Chr13:104386763-104580101 (-)
DBA/2J MGP_DBA2J_G0020674
 protein coding gene Chr13:93572140-93752801 (-)
FVB/NJ MGP_FVBNJ_G0020655
 protein coding gene Chr13:92353555-92532315 (-)
LP/J MGP_LPJ_G0020749
 protein coding gene Chr13:97573048-97777973 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020683
 protein coding gene Chr13:104815934-105007110 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021273
 protein coding gene Chr13:96064797-96261572 (-)
PWK/PhJ MGP_PWKPhJ_G0019861
 protein coding gene Chr13:92357099-92540291 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019685
 protein coding gene Chr13:92350362-92543403 (-)
WSB/EiJ MGP_WSBEiJ_G0020166
 protein coding gene Chr13:96563108-96749016 (-)



Homology
more
  • Human Ortholog
    SV2C, synaptic vesicle glycoprotein 2C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SV2C, synaptic vesicle glycoprotein 2C
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 22987
    neXtProt AC: NX_Q496J9
    UniProt: Q496J9

  • Chr Location
    5q13.3; chr5:75847463-76353939 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit hypoactivity and increased anxiety-related response.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    118
  • Tissues
    104
  • cDNA Data
    7
  • Literature Summary
    12
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75209 NCBI Gene Model | MGI Sequence Detail 173135 C57BL/6J ±  kb
transcript NM_029210 RefSeq | MGI Sequence Detail 4252 C57BL/6  
polypeptide Q69ZS6 UniProt | EBI | MGI Sequence Detail 727 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145291
References
more
  • Summaries
    All 51
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:36947 Ahnert-Hilger G, et al., Synaptobrevin is essential for secretion but not for the development of synaptic processes. Eur J Cell Biol. 1996 May;70(1):1-11
  • Latest
    J:260349 Dunn AR, et al., Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain. Brain Res. 2017 Dec 21;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
03/13/2019
MGI 6.13 		The Jackson Laboratory