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Lemd1 Gene Detail
Summary
  • Symbol
    Lemd1
  • Name
    LEM domain containing 1
  • Synonyms
    4930540I23Rik, 6430514M23Rik, LEMP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922403
    NCBI Gene: 213409
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:132118361-132185120 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 57.24 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922403
 protein coding gene Chr1:132118361-132186965 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016467
 protein coding gene Chr1:135659176-135733154 (+)
A/J MGP_AJ_G0016450
 protein coding gene Chr1:130634518-130702102 (+)
AKR/J MGP_AKRJ_G0016415
 protein coding gene Chr1:134472789-134546967 (+)
BALB/cJ MGP_BALBcJ_G0016410
 protein coding gene Chr1:130956942-131034429 (+)
C3H/HeJ MGP_C3HHeJ_G0016236
 protein coding gene Chr1:134624876-134695555 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016871
 protein coding gene Chr1:140698363-140771337 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014582
 protein coding gene Chr1:123778852-123845533 (+)
CAST/EiJ MGP_CASTEiJ_G0015816
 protein coding gene Chr1:133621255-133691380 (+)
CBA/J MGP_CBAJ_G0016208
 protein coding gene Chr1:145495345-145577229 (+)
DBA/2J MGP_DBA2J_G0016315
 protein coding gene Chr1:129597615-129664837 (+)
FVB/NJ MGP_FVBNJ_G0016314
 protein coding gene Chr1:128223579-128296974 (+)
LP/J MGP_LPJ_G0016386
 protein coding gene Chr1:136968311-137043315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016339
 protein coding gene Chr1:151311077-151381625 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016907
 protein coding gene Chr1:134230516-134304323 (+)
PWK/PhJ MGP_PWKPhJ_G0015602
 protein coding gene Chr1:128581229-128653706 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015389
 protein coding gene Chr1:133176315-133260939 (+)
WSB/EiJ MGP_WSBEiJ_G0015878
 protein coding gene Chr1:134223238-134295953 (+)



Homology
more
  • Human Ortholog
    LEMD1, LEM domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LEMD1, LEM domain containing 1
  • Synonyms
    CT50, LEMP-1
  • Links
    NCBI Gene ID: 93273
    neXtProt AC: NX_Q68G75
    UniProt: Q68G75

  • Chr Location
    1q32.1; chr1:205381378-205455954 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    49
  • Chemically induced (other)
    2
  • Gene trapped
    45
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Lemd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 213409 NCBI Gene Model | MGI Sequence Detail 66760 C57BL/6J ±  kb
transcript NM_001311102 RefSeq | MGI Sequence Detail 1149 C57BL/6  
polypeptide Q14C37 UniProt | EBI | MGI Sequence Detail 129 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 10

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138235, MGI:3026997
References
more
  • Summaries
    All 34
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory