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Rasd2
Gene Detail
 Symbol
Name
ID
Rasd2
RASD family, member 2
MGI:1922391
Synonyms 4930526B11Rik, Rhes, TEM2, TEM-2
Feature Type protein coding gene
Genetic Map
Chromosome 8
35.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:75213944-75224113 bp, + strand
From VEGA annotation of GRCm38

  10170 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8628  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Rasd2

Human
homologs
Human Homolog RASD2, RASD family, member 2
NCBI Gene ID 23551
neXtProt AC  NX_Q96D21
Human Synonyms  MGC:4834, Rhes, TEM2
Human Chr (Location)  22q13.1; chr22:35540507-35554001 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
 
Mice homozygous for a knock-out allele display reduced body weight, impaired motor coordination, hypoactivity, and a gender-dependent increase in anxiety levels.
 
Interactions
Rasd2 interacts with 211 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process behavior, GTP catabolic process, ...
Component membrane, plasma membrane
Function G-protein beta-subunit binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) Genomic(1) cDNA(15)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034050 (Evidence)
Ensembl Gene ModelENSMUSG00000034472 (Evidence)
Entrez Gene75141 (Evidence)
UniGene179267
DFCITC1590649, TC1597864
DoTSDT.55155941, DT.60109419
NIA Mouse Gene IndexU009510
Consensus CDS ProjectCCDS52602.1
International Mouse Knockout Project StatusRasd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034050 VEGA Gene Model | MGI Sequence Detail 10170 C57BL/6J ±  kb
transcript OTTMUST00000085986 VEGA | MGI Sequence Detail 2810 Not Applicable 
polypeptide OTTMUSP00000046496 VEGA | MGI Sequence Detail 266 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013751 GTP-binding protein Rhes
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:201373 Harrison LM, et al., Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum. Neuroscience. 2013 Apr 16;236:21-30
All references(39)
Other
accession IDs
MGI:2142722

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory