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Rnase10
Gene Detail
Symbol

Name
ID
Rnase10
ribonuclease, RNase A family, 10 (non-active)
MGI:1922269
Synonyms
4930474F22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
26.34 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:51007751-51010758 bp, + strand
From Ensembl annotation of GRCm38

  3008 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19166  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase10

Human
homologs
Human Homolog   RNASE10, ribonuclease, RNase A family, 10 (non-active)
NCBI Gene ID 338879
neXtProt AC  NX_Q5GAN6
Human Synonyms  RAH1, RNASE9
Human Chr (Location)  14q11.2; chr14:20505537-20511155 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
 
Homozygous disruption of this gene leads to decreased bone mineral density, alterations in B cell, T cell and NK cell number, and abnormal circulating glucose, creatinine, chloride and serum albumin levels.
 
Interactions
Rnase10 interacts with 127 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell adhesion, epithelial cell morphogenesis, ...
Component extracellular region
Function endonuclease activity, nucleic acid binding, ...
External Resources: FuncBase
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000021872 (Evidence)
Entrez Gene75019 (Evidence)
DFCITC1588877
DoTSDT.101709183, DT.60106877
NIA Mouse Gene IndexU015578
Consensus CDS ProjectCCDS27030.1, CCDS49480.1
International Mouse Knockout Project StatusRnase10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021872 Ensembl Gene Model | MGI Sequence Detail 3008 C57BL/6J ±  kb
transcript ENSMUST00000022424 Ensembl | MGI Sequence Detail 1630 Not Applicable 
polypeptide ENSMUSP00000022424 Ensembl | MGI Sequence Detail 245 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023412 Ribonuclease A-domain
Protein Ontology PR:000014043 ribonuclease-like protein 10
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:216935 Xu B, et al., PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18643-8
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory