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Usp47 Gene Detail
Summary
  • Symbol
    Usp47
  • Name
    ubiquitin specific peptidase 47
  • Synonyms
    4930502N04Rik, A630020C16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922246
    NCBI Gene: 74996
  • Gene Overview
    MyGene.info: USP47
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:112023483-112111386 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 58.74 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    628 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922246
 protein coding gene Chr7:112023483-112111661 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032866
 protein coding gene Chr7:115564351-115666058 (+)
A/J MGP_AJ_G0032849
 protein coding gene Chr7:112700518-112789915 (+)
AKR/J MGP_AKRJ_G0032781
 protein coding gene Chr7:115536357-115624446 (+)
BALB/cJ MGP_BALBcJ_G0032854
 protein coding gene Chr7:112380667-112468414 (+)
C3H/HeJ MGP_C3HHeJ_G0032564
 protein coding gene Chr7:115518024-115617962 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033360
 protein coding gene Chr7:120305310-120403536 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030332
 protein coding gene Chr7:114300825-114390322 (+)
CAST/EiJ MGP_CASTEiJ_G0031892
 protein coding gene Chr7:107134767-107226517 (+)
CBA/J MGP_CBAJ_G0032537
 protein coding gene Chr7:124258783-124354960 (+)
DBA/2J MGP_DBA2J_G0032689
 protein coding gene Chr7:110785891-110875453 (+)
FVB/NJ MGP_FVBNJ_G0032642
 protein coding gene Chr7:110632072-110722460 (+)
LP/J MGP_LPJ_G0032783
 protein coding gene Chr7:117082077-117174020 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032674
 protein coding gene Chr7:125863360-125969638 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033380
 protein coding gene Chr7:114537217-114630383 (+)
PWK/PhJ MGP_PWKPhJ_G0031599
 protein coding gene Chr7:103623558-103712348 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031447
 protein coding gene Chr7:101286749-101381998 (+)
WSB/EiJ MGP_WSBEiJ_G0032005
 protein coding gene Chr7:115398280-115489720 (+)



Homology
more
  • Human Ortholog
    USP47, ubiquitin specific peptidase 47
  • Vertebrate Orthologs
    9
  • Human Ortholog
    USP47, ubiquitin specific peptidase 47
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TRFP
  • Links
    NCBI Gene ID: 55031
    neXtProt AC: NX_Q96K76
    UniProt: Q96K76

  • Chr Location
    11p15.3; chr11:11841423-11959325 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 9929
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: USP47
  • Gene Tree
    Usp47
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mouse embryonic fibroblasts from mice homozygous for a gene trap allele exhibit increased sensitivity to UV irradiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    15
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74996 NCBI Gene Model | MGI Sequence Detail 87904 C57BL/6J ±  kb
transcript NM_001357952 RefSeq | MGI Sequence Detail 5600 C57BL/6  
polypeptide Q8BY87 UniProt | EBI | MGI Sequence Detail 1376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444648
References
more
  • Summaries
    All 48
    Gene Ontology 6
    Phenotypes 21
  • Earliest
    J:61682 Hagiwara N, et al., Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4180-5
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/10/2019
MGI 6.14 		The Jackson Laboratory