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Usp47 Gene Detail
Summary
  • Symbol
    Usp47
  • Name
    ubiquitin specific peptidase 47
  • Synonyms
    4930502N04Rik, A630020C16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922246
    NCBI Gene: 74996
  • Gene Overview
    MyGene.info: USP47
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr7:112023504-112111661 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      88158 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 58.74 cM, cytoband F2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    USP47, ubiquitin specific peptidase 47
  • Vertebrate Orthologs
    9
  • Human Ortholog
    USP47, ubiquitin specific peptidase 47
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TRFP
  • Links
    NCBI Gene ID: 55031
    neXtProt AC: NX_Q96K76
    UniProt: Q96K76

  • Chr Location
    11p15.3; chr11:11841423-11959325 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 9929
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: USP47
  • Gene Tree
    Usp47
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mouse embryonic fibroblasts from mice homozygous for a gene trap allele exhibit increased sensitivity to UV irradiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    14
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060217 VEGA Gene Model | MGI Sequence Detail 88158 C57BL/6J ±  kb
transcript OTTMUST00000147394 VEGA | MGI Sequence Detail 5816 Not Applicable  
polypeptide OTTMUSP00000076702 VEGA | MGI Sequence Detail 1376 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    629 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444648
References
more
  • Summaries
    All 48
    Gene Ontology 6
    Phenotypes 21
  • Earliest
    J:61682 Hagiwara N, et al., Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4180-5
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/15/2018
MGI 6.12 		The Jackson Laboratory