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Pmis2 Gene Detail
Summary
  • Symbol
    Pmis2
  • Name
    PMIS2 transmembrane protein
  • Synonyms
    1700071L20Rik, 4930479M11Rik
Location &
Maps
more
  • Sequence Map
    Chr7:30670722-30671605 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 19.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922177
protein coding gene Chr7:30670722-30671605 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032038
protein coding gene Chr7:29688226-29689108 (-)
A/J MGP_AJ_G0032015
protein coding gene Chr7:28878060-28878938 (-)
AKR/J MGP_AKRJ_G0031948
protein coding gene Chr7:29613970-29614850 (-)
BALB/cJ MGP_BALBcJ_G0032022
protein coding gene Chr7:29066851-29067729 (-)
C3H/HeJ MGP_C3HHeJ_G0031741
protein coding gene Chr7:30072264-30073147 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032488
protein coding gene Chr7:30646533-30647416 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029538
protein coding gene Chr7:29905585-29906448 (-)
CAST/EiJ MGP_CASTEiJ_G0031075
protein coding gene Chr7:23328284-23329166 (-)
CBA/J MGP_CBAJ_G0031707
protein coding gene Chr7:32101661-32102544 (-)
DBA/2J MGP_DBA2J_G0031859
protein coding gene Chr7:28607047-28607930 (-)
FVB/NJ MGP_FVBNJ_G0031816
protein coding gene Chr7:28736135-28737018 (-)
LP/J MGP_LPJ_G0031940
protein coding gene Chr7:29994662-29995543 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031852
protein coding gene Chr7:31344528-31345406 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032516
protein coding gene Chr7:29122123-29123004 (-)
PWK/PhJ MGP_PWKPhJ_G0030799
protein coding gene Chr7:23646988-23647869 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030634
protein coding gene Chr7:20133391-20134326 (-)
WSB/EiJ MGP_WSBEiJ_G0031185
protein coding gene Chr7:29510246-29511129 (-)



Homology
more
  • Human Ortholog
    PMIS2, PMIS2 transmembrane protein
  • Human Ortholog
    PMIS2, PMIS2 transmembrane protein
    Orthology source: HGNC
  • Synonyms
    IFITMD9
  • Links
    NCBI Gene ID: 111216276
    UniProt: A0A1W2PS18

  • Chr Location
    19q13.12

  • HCOP
    human homology predictions: PMIS2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal sperm physiology and male infertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 74927 NCBI Gene Model | MGI Sequence Detail 884 C57BL/6J ±  kb
transcript NR_027848 RefSeq | MGI Sequence Detail 720 C57BL/6  
polypeptide Q8CES1 UniProt | EBI | MGI Sequence Detail 96 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007593 CD225/Dispanin family
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 2
Other
Accession IDs
less
MGI:1920744
References
more
  • Summaries
    All 19
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:185714 Yamaguchi R, et al., Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa. Mol Biol Cell. 2012 Jul;23(14):2671-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory