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Iqca Gene Detail
Summary
  • Symbol
    Iqca
  • Name
    IQ motif containing with AAA domain
  • Synonyms
    4930465P12Rik, 4930585L22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922168
    NCBI Gene: 74918
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:90042132-90153401 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 45.08 cM, cytoband C5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    733 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922168
protein coding gene Chr1:90042132-90153436 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016293
protein coding gene Chr1:91508066-91625947 (-)
A/J MGP_AJ_G0016274
protein coding gene Chr1:88242209-88350525 (-)
AKR/J MGP_AKRJ_G0016235
protein coding gene Chr1:90843725-90962286 (-)
BALB/cJ MGP_BALBcJ_G0016230
protein coding gene Chr1:88401760-88513006 (-)
C3H/HeJ MGP_C3HHeJ_G0016059
protein coding gene Chr1:91059516-91173704 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016689
protein coding gene Chr1:95054833-95180502 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014407
protein coding gene Chr1:82521220-82640472 (-)
CAST/EiJ MGP_CASTEiJ_G0015644
protein coding gene Chr1:90383818-90500404 (-)
CBA/J MGP_CBAJ_G0016035
protein coding gene Chr1:98102355-98221660 (-)
DBA/2J MGP_DBA2J_G0016138
protein coding gene Chr1:87469345-87580402 (-)
FVB/NJ MGP_FVBNJ_G0016137
protein coding gene Chr1:86484639-86597959 (-)
LP/J MGP_LPJ_G0016209
protein coding gene Chr1:92650295-92769928 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016162
protein coding gene Chr1:101374176-101494455 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016729
protein coding gene Chr1:90873256-90987706 (-)
PWK/PhJ MGP_PWKPhJ_G0015428
protein coding gene Chr1:86862310-86974762 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015211
protein coding gene Chr1:89782777-89900588 (-)
WSB/EiJ MGP_WSBEiJ_G0015702
protein coding gene Chr1:90606595-90722654 (-)



Homology
more
  • Human Ortholog
    IQCA1, IQ motif containing with AAA domain 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IQCA1, IQ motif containing with AAA domain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    4930465P12Rik, DRC11, IQCA
  • Links
    NCBI Gene ID: 79781
    neXtProt AC: NX_Q86XH1
    UniProt: Q86XH1

  • Chr Location
    2q37.2-q37.3; chr2:236324147-236507558 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 49784
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IQCA1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026301 Ensembl Gene Model | MGI Sequence Detail 111270 C57BL/6J ±  kb
transcript ENSMUST00000212394 Ensembl | MGI Sequence Detail 2574 Not Applicable  
polypeptide ENSMUSP00000148643 Ensembl | MGI Sequence Detail 857 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923141, MGI:3035497
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:270210 Loo L, et al., Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory