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Ccdc181 Gene Detail
Summary
  • Symbol
    Ccdc181
  • Name
    coiled-coil domain containing 181
  • Synonyms
    4930455F23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922145
    NCBI Gene: 74895
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:164275598-164287847 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 71.59 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922145
protein coding gene Chr1:164275585-164287847 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016682
protein coding gene Chr1:169711567-169723825 (+)
A/J MGP_AJ_G0016663
protein coding gene Chr1:162781153-162793415 (+)
AKR/J MGP_AKRJ_G0016629
protein coding gene Chr1:167720170-167732422 (+)
BALB/cJ MGP_BALBcJ_G0016624
protein coding gene Chr1:163285016-163297270 (+)
C3H/HeJ MGP_C3HHeJ_G0016448
protein coding gene Chr1:167916307-167928573 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017085
protein coding gene Chr1:175397602-175409864 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014794
protein coding gene Chr1:154762351-154774780 (+)
CAST/EiJ MGP_CASTEiJ_G0016028
protein coding gene Chr1:167552670-167564937 (+)
CBA/J MGP_CBAJ_G0016423
protein coding gene Chr1:181649610-181661864 (+)
DBA/2J MGP_DBA2J_G0016529
protein coding gene Chr1:161674716-161687107 (+)
FVB/NJ MGP_FVBNJ_G0016527
protein coding gene Chr1:160135803-160148016 (+)
LP/J MGP_LPJ_G0016600
protein coding gene Chr1:170792198-170804468 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016552
protein coding gene Chr1:189142507-189154738 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017121
protein coding gene Chr1:167563456-167575699 (+)
PWK/PhJ MGP_PWKPhJ_G0015814
protein coding gene Chr1:160865559-160878300 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015601
protein coding gene Chr1:166432561-166445001 (+)
WSB/EiJ MGP_WSBEiJ_G0016090
protein coding gene Chr1:167716749-167729029 (+)



Homology
more
  • Human Ortholog
    CCDC181, coiled-coil domain containing 181
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CCDC181, coiled-coil domain containing 181
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1orf114
  • Links
    NCBI Gene ID: 57821
    neXtProt AC: NX_Q5TID7
    UniProt: Q5TID7

  • Chr Location
    1q24.2; chr1:169394870-169462221 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ccdc181
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74895 NCBI Gene Model | MGI Sequence Detail 12250 C57BL/6J ±  kb
transcript NM_029115 RefSeq | MGI Sequence Detail 1938 C57BL/6  
polypeptide Q80ZU5 UniProt | EBI | MGI Sequence Detail 509 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026687 Coiled-coil domain-containing protein 181
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 2
Other
Accession IDs
less
MGI:2138234
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:241007 Schwarz T, et al., Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia. Eur J Cell Biol. 2017 May;96(3):276-288

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory